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NH2-PEG-NH2 (MW 5000)

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Catalog No. TCL-01642

NH2-PEG-NH2 (MW:5000) is a polyethylene glycol derivative containing two primary amine groups. These amine groups can rapidly react with activated carboxylic acids or carboxyl groups (such as NHS esters) to form stable amide bonds. The PEGylation of NH2-PEG-NH2 enhances solubility and stability while reducing the immunogenicity of peptides and proteins, making it primarily used for modifying proteins, peptides, and other substances.

NH2-PEG-NH2 (MW 5000)
Other Forms of NH2-PEG-NH2 (MW 5000):

NH2-PEG-NH2 (MW 5000)

😃Good
Catalog No. TCL-01642
NH2-PEG-NH2 (MW:5000) is a polyethylene glycol derivative containing two primary amine groups. These amine groups can rapidly react with activated carboxylic acids or carboxyl groups (such as NHS esters) to form stable amide bonds. The PEGylation of NH2-PEG-NH2 enhances solubility and stability while reducing the immunogenicity of peptides and proteins, making it primarily used for modifying proteins, peptides, and other substances.
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
NH2-PEG-NH2 (MW:5000) is a polyethylene glycol derivative containing two primary amine groups. These amine groups can rapidly react with activated carboxylic acids or carboxyl groups (such as NHS esters) to form stable amide bonds. The PEGylation of NH2-PEG-NH2 enhances solubility and stability while reducing the immunogenicity of peptides and proteins, making it primarily used for modifying proteins, peptides, and other substances.
Chemical Properties
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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% Saline/PBS/ddH2O

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

956496-54-1
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