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ICG-carboxylic acid

Name: ICG-carboxylic acid
Brand: TargetMol
SKU: T39254
Price: 50 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T39254Cas No. 181934-09-8

ICG-carboxylic acid is a near-infrared (NIR) fluorocein dye and ICG derivative. ICG (Indocyanine Green) is a fluorescent dye for medical diagnostics with Ex/Em = 790/815 nm, applicable for blood flow measurement and angiography. ICG may also be conjugated to targeted antibodies for tumour cell ablation, such as PANC-1 and BxPC-3.

ICG-carboxylic acid

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Purity: 96.12%

Catalog No. T39254Cas No. 181934-09-8

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$50	-	In Stock
5 mg	$149	-	In Stock
10 mg	$240	-	In Stock
25 mg	$480	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:96.12%

Appearance:Solid

Color:Green

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	ICG-carboxylic acid is a near-infrared (NIR) fluorocein dye and ICG derivative. ICG (Indocyanine Green) is a fluorescent dye for medical diagnostics with Ex/Em = 790/815 nm, applicable for blood flow measurement and angiography. ICG may also be conjugated to targeted antibodies for tumour cell ablation, such as PANC-1 and BxPC-3.
In vitro	Indocyanine green (ICG), a water-soluble compound renowned for its proven fluorescence properties, is extensively and securely utilized in medical diagnostics. Its application in fluorescence-guided surgery facilitates the identification of critical anatomical features, notably intra-abdominal tumors[1].

Chemical Properties

Molecular Weight	730.95
Formula	C₄₅H₅₀N₂O₅S
Cas No.	181934-09-8
Smiles	O=C(O)CCCCCN1C=2C=CC=3C=CC=CC3C2C(C1=CC=CC=CC=CC4=[N+](C=5C=CC=6C=CC=CC6C5C4(C)C)CCCCS(=O)(=O)[O-])(C)C
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from direct sunlight | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 40 mg/mL (54.72 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3681 mL	6.8404 mL	13.6808 mL	68.4041 mL
5 mM	0.2736 mL	1.3681 mL	2.7362 mL	13.6808 mL
10 mM	0.1368 mL	0.6840 mL	1.3681 mL	6.8404 mL
20 mM	0.0684 mL	0.3420 mL	0.6840 mL	3.4202 mL
50 mM	0.0274 mL	0.1368 mL	0.2736 mL	1.3681 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

ICG-carboxylic acid