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YM 218

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Catalog No. T29177Cas No. 387816-81-1
Alias YM-218, YM218

YM 218 is a novel, potent, selective antagonist of nonpeptide vasopressin V1A receptor.

YM 218

YM 218

😃Good
Catalog No. T29177Alias YM-218, YM218Cas No. 387816-81-1
YM 218 is a novel, potent, selective antagonist of nonpeptide vasopressin V1A receptor.
Pack SizePriceAvailabilityQuantity
25 mg$2,4203-6 months
50 mg$3,1803-6 months
100 mg$4,3003-6 months
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Product Introduction

Bioactivity
Description
YM 218 is a novel, potent, selective antagonist of nonpeptide vasopressin V1A receptor.
Targets&IC50
V1b receptor (rat pituitary):1510 nM (Ki), V2 receptor (rat kidney):72.2 nM (Ki), V1a receptor(rat liver):0.5 nM (Ki)
SynonymsYM-218, YM218
Chemical Properties
Molecular Weight616.7
FormulaC35H38F2N4O4
Cas No.387816-81-1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

YM 218
Related Tags: buy YM 218 | purchase YM 218 | YM 218 cost | order YM 218 | YM 218 chemical structure | YM 218 formula | YM 218 molecular weight
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