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Gly-Gly-AMC

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Catalog No. T82281Cas No. 208645-74-3
Alias H-Gly-Gly-AMC

Gly-Gly-AMC (H-Gly-Gly-AMC) is a fluorogenic substrate for cathepsin C, used for quantifying cathepsin C activity.

Gly-Gly-AMC

Gly-Gly-AMC

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Catalog No. T82281Alias H-Gly-Gly-AMCCas No. 208645-74-3
Gly-Gly-AMC (H-Gly-Gly-AMC) is a fluorogenic substrate for cathepsin C, used for quantifying cathepsin C activity.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$11335 days35 days
5 mg$49335 days35 days
10 mg$86235 days35 days
25 mg$1,92035 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Gly-Gly-AMC (H-Gly-Gly-AMC) is a fluorogenic substrate for cathepsin C, used for quantifying cathepsin C activity.
In vitro
Gly-Gly-AMC is subject to hydrolysis at minimal levels by cell extracts from SW480 and T47D [1].
SynonymsH-Gly-Gly-AMC
Chemical Properties
Molecular Weight289.29
FormulaC14H15N3O4
Cas No.208645-74-3
SmilesO=C1OC=2C=C(C=CC2C(=C1)C)NC(=O)CNC(=O)CN
SequenceH-Gly-Gly-AMC
Sequence ShortGG
Storage & Solubility Information
Storagekeep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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