keep away from moisture,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
3-Hydroxykynurenine (3-hydroxy-DL-Kynurenine) is an active metabolite of tryptophan and inhibits yeast and rat liver aldehyde dehydrogenase by 97 and 69%.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 61.00 | |
5 mg | Inquiry | $ 147.00 | |
10 mg | Inquiry | $ 228.00 | |
25 mg | Inquiry | $ 383.00 | |
50 mg | Inquiry | $ 569.00 | |
100 mg | Inquiry | $ 813.00 | |
500 mg | Inquiry | $ 1,630.00 |
Description | 3-Hydroxykynurenine (3-hydroxy-DL-Kynurenine) is an active metabolite of tryptophan and inhibits yeast and rat liver aldehyde dehydrogenase by 97 and 69%. |
In vitro | In CD3/CD28 bead-stimulated CD4+ T cells, 3-Hydroxykynurenine (0-100 μM) dose-dependently inhibits CD4+ T-cell proliferation (IC50 = 70 μM). 3-Hydroxykynurenine (0-100 μM) dose-dependently induces significant CD4+ T-cell-mediated cell[3]. |
In vivo | In BALB/c (H2d) mice, 3-Hydroxykynurenine (560 mg/kg; i.p.) significantly prolongs graft survival whether administered between days 1 to 7, days 7 to 14, or days 1 to 14[3]. |
Synonyms | 3-hydroxy-DL-Kynurenine, DL-3-Hydroxykynurenine |
Molecular Weight | 224.21 |
Formula | C10H12N2O4 |
CAS No. | 484-78-6 |
keep away from moisture,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 1.4 mg/mL (6 mM), Sonication and heating to 60℃ are recommended.
Ethanol: 2 mg/mL
DMF: 0.5 mg/mL
PBS (pH 7.2): 0.5 mg/mL
You can also refer to dose conversion for different animals. More
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3-Hydroxykynurenine 484-78-6 Others 3-hydroxy-DL-Kynurenine DL-3-Hydroxykynurenine inhibitor inhibit