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Anti-Cadherin 6/CDH6 Antibody (2H804) (Synonyms: K-cadherin, KCAD, CDH6, Cadherin-6, Cadherin6, CAD6)

Name: Anti-Cadherin 6/CDH6 Antibody (2H804)
Brand: TargetMol
SKU: TMAY-00363
Rating: 4.5 (1 reviews)

Catalog No. TMAY-00363 Copy Product Info

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Anti-Cadherin 6/CDH6 Antibody (2H804) is a Mouse antibody targeting Cadherin 6/CDH6. Anti-Cadherin 6/CDH6 Antibody (2H804) can be used in ELISA.

Anti-Cadherin 6/CDH6 Antibody (2H804)

Copy Product Info

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Catalog No. TMAY-00363

Synonyms K-cadherin, KCAD, CDH6, Cadherin-6, Cadherin6, CAD6

Anti-Cadherin 6/CDH6 Antibody (2H804) is a Mouse antibody targeting Cadherin 6/CDH6. Anti-Cadherin 6/CDH6 Antibody (2H804) can be used in ELISA.

Anti-Cadherin 6/CDH6 Antibody
(2H804)

Pack Size	Price	USA Stock	Global Stock	Quantity
100 μL	$198	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-Cadherin 6/CDH6 Antibody (2H804) is a Mouse antibody targeting Cadherin 6/CDH6. Anti-Cadherin 6/CDH6 Antibody (2H804) can be used in ELISA.
Synonyms	K-cadherin, KCAD, CDH6, Cadherin-6, Cadherin6, CAD6
Ig Type	Mouse IgG1
Clone	2H804
Reactivity	Human
Specificity	Human Cadherin-6/K-cadherin
Application	ELISA
Recommended Dose	ELISA: 1:1000-1:2000
Antibody Type	Monoclonal
Host Species	Mouse
Construction	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human K Cadherin / CDH6 (rh K Cadherin / CDH6; TMPY-01050; NP_004923.1; Met1-Ala615). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	Cadherins are a family of calcium-dependent, cell-cell adhesion molecules that play an important morpho regulatory role in a wide variety of tissues. Alterations in cadherin function have been implicated in tumor progression in a number of adenocarcinomas. Cadherin-6 (CDH6), also known as K-cadherin (KCAD), is a type-II classic cadherin cell-cell adhesion molecules, which are expressed in graded or areal patterns, as well as layer-specific patterns, in the cortical plate. Human Cadherin-6 is synthesized as a 790 aa type I transmembrane glycoprotein that contains an 18 aa signal peptide, a 35 aa propeptide, a 562 aa extracellular region, a 21 aa transmembrane segment, and a 154 aa cytoplasmic domain. There are five cadherin domains of approximately 110 aa each in the extracellular region. Cadherin-6 is highly expressed in brain, cerebellum, and kidney, and may contribute to the formation of the segmental structure of the early brain, as well as the development of renal proximal tubules. Weak expression is also detected lung, pancreas, and gastric mucosa. Additionally, it is specifically expressed in the proximal tubule of normal kidneys and in renal cell cancer. Thus, Cadherin-6 is a new prognostic factor for renal cancer.

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	Recombinant Protein: Human K Cadherin / CDH6 Protein (TMPY-01050)
Antigen Species	Human

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Keywords

CDH-6CDH 6CAD-6CAD 6

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