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Dnp-RPLALWRS TFA

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Catalog No. T207438

Dnp-RPLALWRS TFA is a fluorescent peptide substrate designed specifically for human matrilysin (MMP-7). Upon enzymatic cleavage at the alanine-leucine bond, the release of the Dnp group alleviates fluorescence quenching, enabling real-time quantitative analysis of MMP-7 activity by enhancing tryptophan emission. This compound offers a sensitive and efficient method for kinetic studies and inhibitor screening.

Dnp-RPLALWRS TFA
Other Forms of Dnp-RPLALWRS TFA:
Dnp-RPLALWRS (trifluoroacetate salt)T36363
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Dnp-RPLALWRS TFA

😃Good
Catalog No. T207438
Dnp-RPLALWRS TFA is a fluorescent peptide substrate designed specifically for human matrilysin (MMP-7). Upon enzymatic cleavage at the alanine-leucine bond, the release of the Dnp group alleviates fluorescence quenching, enabling real-time quantitative analysis of MMP-7 activity by enhancing tryptophan emission. This compound offers a sensitive and efficient method for kinetic studies and inhibitor screening.
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Product Introduction

Bioactivity
Description
Dnp-RPLALWRS TFA is a fluorescent peptide substrate designed specifically for human matrilysin (MMP-7). Upon enzymatic cleavage at the alanine-leucine bond, the release of the Dnp group alleviates fluorescence quenching, enabling real-time quantitative analysis of MMP-7 activity by enhancing tryptophan emission. This compound offers a sensitive and efficient method for kinetic studies and inhibitor screening.
Chemical Properties
FormulaC54H78F3N17O16
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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