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(±)16,17-EDT (Synonyms: (±)-Dihomo-16,17-EET, (±)16,17-Epoxydocosatrienoic Acid, (±)16,17-EpDoTrE)

Name: (±)16,17-EDT
Brand: TargetMol
SKU: T83869
Rating: 4.5 (1 reviews)

Catalog No. T83869 Copy Product Info

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(±)16,17-EDT, an oxylipin metabolite of adrenic acid produced through the cytochrome P450 (CYP) pathway, effectively induces dilation in isolated porcine arterioles (EC50 = 11 pM) and promotes relaxation of isolated bovine coronary arteries previously contracted by the TP receptor agonist U-46619.

(±)16,17-EDT

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Catalog No. T83869

Synonyms (±)-Dihomo-16,17-EET, (±)16,17-Epoxydocosatrienoic Acid, (±)16,17-EpDoTrE

Cas No. 351533-79-4

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Pack Size	Price	USA Stock	Global Stock
25 μg	$178	35 days	35 days
50 μg	$319	35 days	35 days
100 μg	$593	35 days	35 days
500 μg	$2,650	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description	(±)16,17-EDT, an oxylipin metabolite of adrenic acid produced through the cytochrome P450 (CYP) pathway, effectively induces dilation in isolated porcine arterioles (EC50 = 11 pM) and promotes relaxation of isolated bovine coronary arteries previously contracted by the TP receptor agonist U-46619.
Synonyms	(±)-Dihomo-16,17-EET, (±)16,17-Epoxydocosatrienoic Acid, (±)16,17-EpDoTrE

Chemical Properties

Molecular Weight	348.52
Formula	C₂₂H₃₆O₃
Cas No.	351533-79-4
Smiles	OC(CCCCC/C=C\C/C=C\C/C=C\CC1C(O1)CCCCC)=O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 10 mg/mL (28.69 mM), Sonication is recommended.

Solution Preparation Table

Ethanol

	1mg	5mg	10mg	50mg
1 mM	2.8693 mL	14.3464 mL	28.6928 mL	143.4638 mL
5 mM	0.5739 mL	2.8693 mL	5.7386 mL	28.6928 mL
10 mM	0.2869 mL	1.4346 mL	2.8693 mL	14.3464 mL
20 mM	0.1435 mL	0.7173 mL	1.4346 mL	7.1732 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc