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5-chloro Hydrochlorothiazide

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Catalog No. T35842Cas No. 5233-42-1

5-chloro Hydrochlorothiazide is a derivative of hydrochlorothiazide, which is a diuretic and antihypertensive agent that increases renal excretion of sodium, potassium, chloride, and bicarbonate ions by inhibiting tubular reabsorptive mechanisms.

5-chloro Hydrochlorothiazide

5-chloro Hydrochlorothiazide

😃Good
Catalog No. T35842Cas No. 5233-42-1
5-chloro Hydrochlorothiazide is a derivative of hydrochlorothiazide, which is a diuretic and antihypertensive agent that increases renal excretion of sodium, potassium, chloride, and bicarbonate ions by inhibiting tubular reabsorptive mechanisms.
Pack SizePriceAvailabilityQuantity
1 mg$987-10 days
5 mg$4287-10 days
10 mg$8107-10 days
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Product Introduction

Bioactivity
Description
5-chloro Hydrochlorothiazide is a derivative of hydrochlorothiazide, which is a diuretic and antihypertensive agent that increases renal excretion of sodium, potassium, chloride, and bicarbonate ions by inhibiting tubular reabsorptive mechanisms.
Chemical Properties
Molecular Weight332.18
FormulaC7H7Cl2N3O4S2
Cas No.5233-42-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL (1.51 mM), Sonication is recommended.
DMF: 30 mg/mL (90.31 mM), Sonication is recommended.
DMSO: 20 mg/mL (60.21 mM), Sonication is recommended.
Solution Preparation Table
DMF:PBS(pH 7.2)(1:1)/DMSO/DMF
1mg5mg10mg50mg
1 mM3.0104 mL15.0521 mL30.1042 mL150.5208 mL
DMSO/DMF
1mg5mg10mg50mg
5 mM0.6021 mL3.0104 mL6.0208 mL30.1042 mL
10 mM0.3010 mL1.5052 mL3.0104 mL15.0521 mL
20 mM0.1505 mL0.7526 mL1.5052 mL7.5260 mL
50 mM0.0602 mL0.3010 mL0.6021 mL3.0104 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

5-chloro Hydrochlorothiazide5chloro Hydrochlorothiazide5 chloro Hydrochlorothiazide
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