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Hersintuzumab
🥰Excellent
Catalog No. T9901A-1325
Hersintuzumab is a humanized monoclonal antibody targeting the human epidermal growth factor receptor 2 (HER2/ErbB2). By specifically binding to the extracellular domain of HER2, it blocks downstream proliferative signaling pathways (e.g., PI3K/Akt) and mediates antibody-dependent cellular cytotoxicity (ADCC), making it widely used to research therapeutic strategies for HER2-positive malignancies like breast and gastric cancers.
Hersintuzumab
Hersintuzumab
🥰Excellent
Catalog No. T9901A-1325
Hersintuzumab is a humanized monoclonal antibody targeting the human epidermal growth factor receptor 2 (HER2/ErbB2). By specifically binding to the extracellular domain of HER2, it blocks downstream proliferative signaling pathways (e.g., PI3K/Akt) and mediates antibody-dependent cellular cytotoxicity (ADCC), making it widely used to research therapeutic strategies for HER2-positive malignancies like breast and gastric cancers.
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| Description | Hersintuzumab is a humanized monoclonal antibody targeting the human epidermal growth factor receptor 2 (HER2/ErbB2). By specifically binding to the extracellular domain of HER2, it blocks downstream proliferative signaling pathways (e.g., PI3K/Akt) and mediates antibody-dependent cellular cytotoxicity (ADCC), making it widely used to research therapeutic strategies for HER2-positive malignancies like breast and gastric cancers. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | ERBB2/HER2/CD340 |
| Isotype | IgG1 |
| Storage | store at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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