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Acetaminophen (Standard)

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Catalog No. TMSM-0349Cas No. 103-90-2
Alias Paracetamol (Standard), 4'-Hydroxyacetanilide (Standard), 4-Acetamidophenol (Standard)

Acetaminophen (Standard) is a reference standard for acetaminophen used in QC and analytical studies. Acetaminophen inhibits COX-1 and COX-2 (IC₅₀ = 113.7 / 25.8 μM), and has antipyretic and analgesic activity with weak anti-inflammatory effects.

Acetaminophen (Standard)

Acetaminophen (Standard)

😃Good
Catalog No. TMSM-0349Alias Paracetamol (Standard), 4'-Hydroxyacetanilide (Standard), 4-Acetamidophenol (Standard)Cas No. 103-90-2
Acetaminophen (Standard) is a reference standard for acetaminophen used in QC and analytical studies. Acetaminophen inhibits COX-1 and COX-2 (IC₅₀ = 113.7 / 25.8 μM), and has antipyretic and analgesic activity with weak anti-inflammatory effects.
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100 mg$487-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Acetaminophen (Standard) is a reference standard for acetaminophen used in QC and analytical studies. Acetaminophen inhibits COX-1 and COX-2 (IC₅₀ = 113.7 / 25.8 μM), and has antipyretic and analgesic activity with weak anti-inflammatory effects.
In vitro
Acetaminophen (Standard), as an analytical standard-grade compound, is primarily used for content detection. It is commonly employed in qualitative analysis, quantitative determination experiments corresponding to analytical techniques such as liquid chromatography, gas chromatography, and mass spectrometry, as well as in methodological research for various analytical methods.
SynonymsParacetamol (Standard), 4'-Hydroxyacetanilide (Standard), 4-Acetamidophenol (Standard)
Chemical Properties
Molecular Weight151.16
FormulaC8H9NO2
Cas No.103-90-2
SmilesO=C(NC1=CC=C(O)C=C1)C
Relative Density.1.293 g/cm3
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 200 mg/mL (1323.1 mM), Sonication is recommeded.
H2O: 80 mg/mL (529.24 mM), Sonication is recommeded.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM6.6155 mL33.0775 mL66.1551 mL330.7753 mL
5 mM1.3231 mL6.6155 mL13.2310 mL66.1551 mL
10 mM0.6616 mL3.3078 mL6.6155 mL33.0775 mL
20 mM0.3308 mL1.6539 mL3.3078 mL16.5388 mL
50 mM0.1323 mL0.6616 mL1.3231 mL6.6155 mL
100 mM0.0662 mL0.3308 mL0.6616 mL3.3078 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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