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Viltolarsen
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Catalog No. T39455Cas No. 2055732-84-6
Alias NS-065, NCNP-01
Viltolarsen (NS-065/NCNP-01) is a phosphorodiamidate morpholino antisense oligonucleotide that specifically targets exon 53 splicing in the dystrophin gene, used in Duchenne muscular dystrophy (DMD) research.
Viltolarsen
😃Good
Catalog No. T39455Alias NS-065, NCNP-01Cas No. 2055732-84-6
Viltolarsen (NS-065/NCNP-01) is a phosphorodiamidate morpholino antisense oligonucleotide that specifically targets exon 53 splicing in the dystrophin gene, used in Duchenne muscular dystrophy (DMD) research.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $252 | 2-4 weeks | 2-4 weeks | |
| 5 mg | $646 | 2-4 weeks | 2-4 weeks | |
| 10 mg | $1,050 | 2-4 weeks | 2-4 weeks |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction
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Chemical Properties
| Description | Viltolarsen (NS-065/NCNP-01) is a phosphorodiamidate morpholino antisense oligonucleotide that specifically targets exon 53 splicing in the dystrophin gene, used in Duchenne muscular dystrophy (DMD) research. |
| In vitro | Duchenne muscular dystrophy (DMD), a prevalent and fatal muscle-degenerative condition affecting young boys, is caused by mutations in the DMD gene. Exon skipping has gained recognition as a potential treatment strategy for DMD. Antisense oligonucleotides (AONs) are engineered to promote the omission of specific exon(s), aiming to rectify the reading frame and consequently enable the production of dystrophin[1]. |
| Synonyms | NS-065, NCNP-01 |
| Cas No. | 2055732-84-6 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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