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Tris(2,2,2-trifluoroethyl) borate

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Catalog No. T2186Cas No. 659-18-7
Alias SL 75212

Tris(2,2,2-trifluoroethyl) borate (SL 75212) is mostly used in condensation reactions. It has been shown to promote the direct formation of amides from carboxylic acids and amines as well as the formation of imines from amines or amides with carbonyl compounds.

Tris(2,2,2-trifluoroethyl) borate

Tris(2,2,2-trifluoroethyl) borate

😃Good
Catalog No. T2186Alias SL 75212Cas No. 659-18-7
Tris(2,2,2-trifluoroethyl) borate (SL 75212) is mostly used in condensation reactions. It has been shown to promote the direct formation of amides from carboxylic acids and amines as well as the formation of imines from amines or amides with carbonyl compounds.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$46-In Stock
50 mg$81-In Stock
100 mg$138-In Stock
200 mg$209-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Appearance:Liquid
Color:Transparent
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Product Introduction

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Description
Tris(2,2,2-trifluoroethyl) borate (SL 75212) is mostly used in condensation reactions. It has been shown to promote the direct formation of amides from carboxylic acids and amines as well as the formation of imines from amines or amides with carbonyl compounds.
SynonymsSL 75212
Chemical Properties
Molecular Weight307.91
FormulaC6H6BF9O3
Cas No.659-18-7
SmilesFC(F)(F)COB(OCC(F)(F)F)OCC(F)(F)F
Relative Density.1.430 g/cm3 at 25℃
Storage & Solubility Information
StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (146.15 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2477 mL16.2385 mL32.4770 mL162.3851 mL
5 mM0.6495 mL3.2477 mL6.4954 mL32.4770 mL
10 mM0.3248 mL1.6239 mL3.2477 mL16.2385 mL
20 mM0.1624 mL0.8119 mL1.6239 mL8.1193 mL
50 mM0.0650 mL0.3248 mL0.6495 mL3.2477 mL
100 mM0.0325 mL0.1624 mL0.3248 mL1.6239 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
% Tween 80
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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