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Coronatine

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Catalog No. T75600Cas No. 62251-96-1

Coronatine is a toxin and plant growth regulator produced by a bacterium, Pseudomonas syringae, which is structurally similar to jasmonic acid and is able to bind and activate the jasmonic acid receptor, COI1, to inhibit salicylic acid-dependent defense responses; it is also able to promote bacterial invasion and reproduction through stomata.

Coronatine

Coronatine

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Purity: 99.37%
Catalog No. T75600Cas No. 62251-96-1
Coronatine is a toxin and plant growth regulator produced by a bacterium, Pseudomonas syringae, which is structurally similar to jasmonic acid and is able to bind and activate the jasmonic acid receptor, COI1, to inhibit salicylic acid-dependent defense responses; it is also able to promote bacterial invasion and reproduction through stomata.
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1 mg$396-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.37%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Coronatine is a toxin and plant growth regulator produced by a bacterium, Pseudomonas syringae, which is structurally similar to jasmonic acid and is able to bind and activate the jasmonic acid receptor, COI1, to inhibit salicylic acid-dependent defense responses; it is also able to promote bacterial invasion and reproduction through stomata.
In vitro
Methods: Plants were grown on vertical MS plates for 12 days and then transferred to MS plates containing ABA (5 μM) and coronatine (1 μM) or no other chemicals as controls. Rosette leaves were collected 24 hours later for RNA extraction.
Results: Coronatine induced the expression of NAC transcription factor genes (ANAC019, ANAC055, and ANAC072), inhibited abscisic acid-induced stomatal closure, promoted stomatal reopening, and inhibited the accumulation of salicylic acid, thereby weakening the plant's immune response. [1]
Chemical Properties
Molecular Weight319.4
FormulaC18H25NO4
Cas No.62251-96-1
SmilesN(C(=O)C=1[C@@]2([C@](C[C@@H](CC)C1)(C(=O)CC2)[H])[H])[C@]3(C(O)=O)[C@@H](CC)C3
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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