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Ioxilan

Name: Ioxilan
Brand: TargetMol
SKU: T19377
Price: 99 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T19377Cas No. 107793-72-6

Alias Oxilan, Imagenil

Ioxilan (Imagenil) is a tri-iodinated X-ray contrast agent used in computer tomography (CECT) imaging as a biological membrane transparency agent.

Ioxilan

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Purity: 98.34%

Catalog No. T19377Alias Oxilan, ImagenilCas No. 107793-72-6

Ioxilan (Imagenil) is a tri-iodinated X-ray contrast agent used in computer tomography (CECT) imaging as a biological membrane transparency agent.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$99	-	In Stock
1 mL x 10 mM (in DMSO)	$215	8-10 weeks	8-10 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:98.34%

Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description	Ioxilan (Imagenil) is a tri-iodinated X-ray contrast agent used in computer tomography (CECT) imaging as a biological membrane transparency agent.
In vitro	Ioxilan introduces dimethylene as a hydrophobic region masked by hydrophilic hydroxyl, which can reduce osmotic pressure without adversely affecting biological tolerance, and can improve the safety and tolerance of X-ray contrast agents. [2]
In vivo	Ioxilan increased the excretion of albumin, LDH and GGT in rats, resulting in temporary glomerular and tubular dysfunction in rats, but the effect was less than that of diatrizoate and iohexol. [1]
Synonyms	Oxilan, Imagenil

Chemical Properties

Molecular Weight	791.11
Formula	C₁₈H₂₄I₃N₃O₈
Cas No.	107793-72-6
Smiles	O=C(NCCO)C=1C(I)=C(C(=O)NCC(O)CO)C(I)=C(C1I)N(C(=O)C)CC(O)CO
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 200 mg/mL (252.81 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2640 mL	6.3202 mL	12.6405 mL	63.2023 mL
5 mM	0.2528 mL	1.2640 mL	2.5281 mL	12.6405 mL
10 mM	0.1264 mL	0.6320 mL	1.2640 mL	6.3202 mL
20 mM	0.0632 mL	0.3160 mL	0.6320 mL	3.1601 mL
50 mM	0.0253 mL	0.1264 mL	0.2528 mL	1.2640 mL
100 mM	0.0126 mL	0.0632 mL	0.1264 mL	0.6320 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Ioxilan