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NSC61610

Name: NSC61610
Brand: TargetMol
SKU: T28207
Rating: 4.5 (1 reviews)

🥰Excellent

Catalog No. T28207Cas No. 500538-94-3

Alias SMR000528839, SMR 000528839, NSC-61610, MLS000766212, MLS 000766212

NSC61610 is a molecule with anti-inflammatory effects that activates PPARγ in vitro via LANCL2 and adenylate cyclase/cAMP-dependent pathways, downregulates colonic inflammatory gene expression, and promotes regulatory T cell responses, thereby improving experimental colitis.

NSC61610

🥰Excellent

Catalog No. T28207Alias SMR000528839, SMR 000528839, NSC-61610, MLS000766212, MLS 000766212Cas No. 500538-94-3

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Product Introduction

Bioactivity

Description	NSC61610 is a molecule with anti-inflammatory effects that activates PPARγ in vitro via LANCL2 and adenylate cyclase/cAMP-dependent pathways, downregulates colonic inflammatory gene expression, and promotes regulatory T cell responses, thereby improving experimental colitis.
Synonyms	SMR000528839, SMR 000528839, NSC-61610, MLS000766212, MLS 000766212

Chemical Properties

Molecular Weight	548.59
Formula	C₃₄H₂₄N₆O₂
Cas No.	500538-94-3
Smiles	O=C(NC1=CC=CC(=C1)C2=NC=3C=CC=CC3N2)C4=CC=C(C=C4)C(=O)NC5=CC=CC(=C5)C6=NC=7C=CC=CC7N6
Relative Density.	1.410 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (145.83 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8229 mL	9.1143 mL	18.2285 mL	91.1427 mL
5 mM	0.3646 mL	1.8229 mL	3.6457 mL	18.2285 mL
10 mM	0.1823 mL	0.9114 mL	1.8229 mL	9.1143 mL
20 mM	0.0911 mL	0.4557 mL	0.9114 mL	4.5571 mL
50 mM	0.0365 mL	0.1823 mL	0.3646 mL	1.8229 mL
100 mM	0.0182 mL	0.0911 mL	0.1823 mL	0.9114 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc