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Tat-peptide 190-208

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Catalog No. TP3416

Tat-peptide 190-208 is a Tat-tagged cell-penetrating fusion peptide that corresponds to residues 190-208 of rat G3BP1. The Tat sequence from HIV, positioned at the least conserved end of the sequence, facilitates cell permeability. Tat-peptide 190-208 enhances axonal growth and increases the number of axons per neuron, potentially demonstrating intrinsic axonal mechanisms. It may also be employed for ischemic protection during endovascular repair of intracranial aneurysms.

Tat-peptide 190-208
Other Forms of Tat-peptide 190-208:
Tat-peptide 190-208 TFAT78040
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Tat-peptide 190-208

😃Good
Catalog No. TP3416
Tat-peptide 190-208 is a Tat-tagged cell-penetrating fusion peptide that corresponds to residues 190-208 of rat G3BP1. The Tat sequence from HIV, positioned at the least conserved end of the sequence, facilitates cell permeability. Tat-peptide 190-208 enhances axonal growth and increases the number of axons per neuron, potentially demonstrating intrinsic axonal mechanisms. It may also be employed for ischemic protection during endovascular repair of intracranial aneurysms.
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Bioactivity
Description
Tat-peptide 190-208 is a Tat-tagged cell-penetrating fusion peptide that corresponds to residues 190-208 of rat G3BP1. The Tat sequence from HIV, positioned at the least conserved end of the sequence, facilitates cell permeability. Tat-peptide 190-208 enhances axonal growth and increases the number of axons per neuron, potentially demonstrating intrinsic axonal mechanisms. It may also be employed for ischemic protection during endovascular repair of intracranial aneurysms.
In vitro
Tat-peptide 190-208, when applied at concentrations of 10 μM and 20 μM for 24 hours, enhances axon length in isolated DRG cultures at 10 μM and in iMotor neurons at 20 μM. Additionally, a 10 μM concentration of Tat-peptide 190-208 over 3 days increases the total number of axons extending from each neuron.
Chemical Properties
FormulaC142H214N40O57
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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