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Xanomeline tartrate

Name: Xanomeline tartrate
Brand: TargetMol
SKU: T39010
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T39010Cas No. 152854-19-8

Alias LY-246708 tartrate, LY246708 tartrate, LY 246708 tartrate

Xanomeline tartrate (LY 246708 tartrate) is an M1 and M4 mAChR agonist with antipsychotic-like activity that improves cognition and can be used in studies of schizophrenia and Alzheimer's disease.

Xanomeline tartrate

🥰Excellent

Purity: 99.19%

Catalog No. T39010Alias LY-246708 tartrate, LY246708 tartrate, LY 246708 tartrateCas No. 152854-19-8

Xanomeline tartrate (LY 246708 tartrate) is an M1 and M4 mAChR agonist with antipsychotic-like activity that improves cognition and can be used in studies of schizophrenia and Alzheimer's disease.

Pack Size	Price	Availability
2 mg	$30	In Stock
5 mg	$46	In Stock
10 mg	$64	In Stock
25 mg	$98	In Stock
50 mg	$148	In Stock
100 mg	$217	In Stock

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Batch Information

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Purity:99.19%

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COA HPLC HNMR

Product Introduction

Bioactivity

Description	Xanomeline tartrate (LY 246708 tartrate) is an M1 and M4 mAChR agonist with antipsychotic-like activity that improves cognition and can be used in studies of schizophrenia and Alzheimer's disease.
In vitro	Xanomeline tartrate (LY 246708) (0.1-10 μM; CNS4U) shows an overall increase in average firing rate, indicating the functional presence of M1 receptors in hiPSC-derived neurons[1].
In vivo	In Male Cebus apella monkeys, Xanomeline tartrate ( 0.5-3 mg / kg ; s.c. ; 1-3 hours ) can induce salivation and vomiting in some monkeys[3].
Synonyms	LY-246708 tartrate, LY246708 tartrate, LY 246708 tartrate

Chemical Properties

Molecular Weight	431.5
Formula	C₁₈H₂₉N₃O₇S
Cas No.	152854-19-8
Smiles	O[C@@H]([C@H](O)C(O)=O)C(O)=O.CCCCCCOc1nsnc1C1=CCCN(C)C1
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 200 mg/mL (463.50 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3175 mL	11.5875 mL	23.1750 mL	115.8749 mL
5 mM	0.4635 mL	2.3175 mL	4.6350 mL	23.1750 mL
10 mM	0.2317 mL	1.1587 mL	2.3175 mL	11.5875 mL
20 mM	0.1159 mL	0.5794 mL	1.1587 mL	5.7937 mL
50 mM	0.0463 mL	0.2317 mL	0.4635 mL	2.3175 mL
100 mM	0.0232 mL	0.1159 mL	0.2317 mL	1.1587 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc