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Ganoderic acid J

Name: Ganoderic acid J
Brand: TargetMol
SKU: T38396
Price: 139 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T38396 Copy Product Info

Purity: 99.96%

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Ganoderic acid J is a natural lanostane-type triterpenoid isolated from the medicinal fungus Ganoderma lucidum. Since its initial characterization in 1985, Ganoderic acid J has been identified as a bioactive constituent with potent anti-inflammatory activity. As a representative member of the ganoderic acid family, it plays a critical role in modulating immune cell responses and mitigating inflammation. It serves as a significant molecular probe for investigating the pharmacological mechanisms of fungal secondary metabolites in inflammatory diseases

Ganoderic acid J

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Catalog No. T38396

Cas No. 100440-26-4

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Pack Size	Price	USA Stock	Global Stock
1 mg	$139	-	In Stock
5 mg	$347	-	In Stock
10 mg	$562	-	In Stock
25 mg	$889	-	In Stock
1 mL x 10 mM (in DMSO)	$393	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.96%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

In vitro

Ganoderic acid J suppresses LPS-induced NO and pro-inflammatory cytokine production in macrophages. Its anti-inflammatory effects are mediated via modulation of NF-κB or MAPK signaling pathways [2].

Chemical Properties

Molecular Weight	514.66
Formula	C₃₀H₄₂O₇
Cas No.	100440-26-4
Smiles	O=C1C2=C(C(=O)CC3(C)C(CC(O)C23C)C(C)CC(=O)CC(C(=O)O)C)C4(C)CCC(=O)C(C)(C)C4C1
Relative Density.	1.22 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 40.00 mg/mL (77.72 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9430 mL	9.7152 mL	19.4303 mL	97.1515 mL
5 mM	0.3886 mL	1.9430 mL	3.8861 mL	19.4303 mL
10 mM	0.1943 mL	0.9715 mL	1.9430 mL	9.7152 mL
20 mM	0.0972 mL	0.4858 mL	0.9715 mL	4.8576 mL
50 mM	0.0389 mL	0.1943 mL	0.3886 mL	1.9430 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Citations

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Ganoderic acid J