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IAJD97

🥰Excellent
Catalog No. TCL-01228Cas No. 2857089-36-0

IAJD97 is an ionizable amphiphilic Janus dendrimer (pKa = 6.46) employed in creating dendrosome nanoparticles (DNPs) for in vivo mRNA delivery. DNPs made from IAJD97 and containing mRNA for luciferase preferentially target the lymph nodes, spleen, and lungs rather than the liver and heart in mice.

IAJD97

IAJD97

🥰Excellent
Catalog No. TCL-01228Cas No. 2857089-36-0
IAJD97 is an ionizable amphiphilic Janus dendrimer (pKa = 6.46) employed in creating dendrosome nanoparticles (DNPs) for in vivo mRNA delivery. DNPs made from IAJD97 and containing mRNA for luciferase preferentially target the lymph nodes, spleen, and lungs rather than the liver and heart in mice.
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Product Introduction

Bioactivity
Description
IAJD97 is an ionizable amphiphilic Janus dendrimer (pKa = 6.46) employed in creating dendrosome nanoparticles (DNPs) for in vivo mRNA delivery. DNPs made from IAJD97 and containing mRNA for luciferase preferentially target the lymph nodes, spleen, and lungs rather than the liver and heart in mice.
Chemical Properties
Molecular Weight691.04
FormulaC41H74N2O6
Cas No.2857089-36-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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