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BRD3067 FA

Name: BRD3067 FA
Brand: TargetMol
SKU: T30578L
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T30578L

Alias BRD3067 FA(1883657-02-0 Free base)

BRD3067 FA is a structurally negative control for tubastatin A, which prevents it from entering the active site of the enzyme and protects neurons from H2O2.

BRD3067 FA

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Purity: 98.12%

Catalog No. T30578LAlias BRD3067 FA(1883657-02-0 Free base)

BRD3067 FA is a structurally negative control for tubastatin A, which prevents it from entering the active site of the enzyme and protects neurons from H2O2.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$195	In Stock	In Stock
5 mg	$483	In Stock	In Stock
10 mg	$692	In Stock	In Stock
25 mg	$1,080	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:98.12%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	BRD3067 FA is a structurally negative control for tubastatin A, which prevents it from entering the active site of the enzyme and protects neurons from H2O2.
Targets&IC50	HDAC6:15 nM (cell-free assay)
Synonyms	BRD3067 FA(1883657-02-0 Free base)

Chemical Properties

Molecular Weight	395.45
Formula	C₂₂H₂₅N₃O₄
Smiles	O=C(C1=CC=C(CN2C3=C(C4=C2CCN(C4)C)C=CC=C3)C=C1C)NO.OC([H])=O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (632.19 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5288 mL	12.6438 mL	25.2876 mL	126.4382 mL
5 mM	0.5058 mL	2.5288 mL	5.0575 mL	25.2876 mL
10 mM	0.2529 mL	1.2644 mL	2.5288 mL	12.6438 mL
20 mM	0.1264 mL	0.6322 mL	1.2644 mL	6.3219 mL
50 mM	0.0506 mL	0.2529 mL	0.5058 mL	2.5288 mL
100 mM	0.0253 mL	0.1264 mL	0.2529 mL	1.2644 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

BRD3067FA(1883657020Freebase)