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N-Acetyl-L-proline

Name: N-Acetyl-L-proline
Brand: TargetMol
SKU: TN11612
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN11612Cas No. 68-95-1

Alias N-Acetyl-L-proline, Ac-Pro-OH

N-Acetyl-L-proline is a chemically defined derivative of the amino acid L-proline that is widely applied across pharmaceutical formulation development, cosmetic science, and advanced biochemical research due to its distinctive cyclic structure, where it is deliberately employed to improve peptide stability, optimize solubility profiles, enhance membrane permeability, and support drug delivery strategies including experimental evaluation of blood–brain barrier transport while also serving as a robust building block for peptide synthesis, enzyme characterization studies such as angiotensin-converting enzyme investigations, and nutrition-focused cognitive enhancement research.

N-Acetyl-L-proline

😃Good

Purity: 99.02%

Catalog No. TN11612Alias N-Acetyl-L-proline, Ac-Pro-OHCas No. 68-95-1

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
500 mg	$37	-	In Stock
1 g	$55	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.02%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

Synonyms

N-Acetyl-L-proline, Ac-Pro-OH

Chemical Properties

Molecular Weight	157.17
Formula	C₇H₁₁NO₃
Cas No.	68-95-1
Smiles	C(O)(=O)[C@H]1N(C(C)=O)CCC1
Sequence	Ac-Pro-OH
Sequence Short	Ac-P

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (636.25 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.3625 mL	31.8127 mL	63.6254 mL	318.1269 mL
5 mM	1.2725 mL	6.3625 mL	12.7251 mL	63.6254 mL
10 mM	0.6363 mL	3.1813 mL	6.3625 mL	31.8127 mL
20 mM	0.3181 mL	1.5906 mL	3.1813 mL	15.9063 mL
50 mM	0.1273 mL	0.6363 mL	1.2725 mL	6.3625 mL
100 mM	0.0636 mL	0.3181 mL	0.6363 mL	3.1813 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc