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Diethylene glycol

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Catalog No. T21019Cas No. 111-46-6
Alias Glycol ether, Diglycol, Digenos, Diethylenglykol, 2,2'-Oxybisethanol, 2,2'-0xydiethanol

Diethylene glycol (Diethylenglykol) is a nephrotoxic and neurotoxic compound that can cause acute kidney injury (AKI) when ingested in large amounts.

Diethylene glycol

Diethylene glycol

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Purity: 99.89%
Catalog No. T21019Alias Glycol ether, Diglycol, Digenos, Diethylenglykol, 2,2'-Oxybisethanol, 2,2'-0xydiethanolCas No. 111-46-6
Diethylene glycol (Diethylenglykol) is a nephrotoxic and neurotoxic compound that can cause acute kidney injury (AKI) when ingested in large amounts.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 g$37-In Stock
10 g$52-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.89%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Diethylene glycol (Diethylenglykol) is a nephrotoxic and neurotoxic compound that can cause acute kidney injury (AKI) when ingested in large amounts.
SynonymsGlycol ether, Diglycol, Digenos, Diethylenglykol, 2,2'-Oxybisethanol, 2,2'-0xydiethanol
Chemical Properties
Molecular Weight106.12
FormulaC4H10O3
Cas No.111-46-6
SmilesOCCOCCO
Relative Density.1.118 dimensionless. Temperature:20 °C.
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 8 mg/mL (75.39 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM9.4233 mL47.1165 mL94.2329 mL471.1647 mL
5 mM1.8847 mL9.4233 mL18.8466 mL94.2329 mL
10 mM0.9423 mL4.7116 mL9.4233 mL47.1165 mL
20 mM0.4712 mL2.3558 mL4.7116 mL23.5582 mL
50 mM0.1885 mL0.9423 mL1.8847 mL9.4233 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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