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(S,S)-GNE 5729

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Catalog No. T15408LCas No. 2026636-06-4
Alias (S,S)-GNE5729

(S,S)-GNE 5729 is an enantiomer of GNE 5729, widely used in biochemical experiments and drug synthesis research. GNE 5729 is a blood-brain barrier-permeable positive modulator of the NMDAR.

(S,S)-GNE 5729

(S,S)-GNE 5729

🥰Excellent
Purity: 99.48%
Catalog No. T15408LAlias (S,S)-GNE5729Cas No. 2026636-06-4
(S,S)-GNE 5729 is an enantiomer of GNE 5729, widely used in biochemical experiments and drug synthesis research. GNE 5729 is a blood-brain barrier-permeable positive modulator of the NMDAR.
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Purity:99.48%
ee:100%
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Product Introduction

Bioactivity
Description
(S,S)-GNE 5729 is an enantiomer of GNE 5729, widely used in biochemical experiments and drug synthesis research. GNE 5729 is a blood-brain barrier-permeable positive modulator of the NMDAR.
Alias(S,S)-GNE5729
Chemical Properties
Molecular Weight428.2
FormulaC17H10Cl2F3N5O
Cas No.2026636-06-4
SmilesClC1=C(N2C(=NC(CN3N=C(C(F)(F)F)C=C3Cl)=CC2=O)C=C1)[C@@H]4[C@@H](C#N)C4
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (186.83 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3354 mL11.6768 mL23.3536 mL116.7679 mL
5 mM0.4671 mL2.3354 mL4.6707 mL23.3536 mL
10 mM0.2335 mL1.1677 mL2.3354 mL11.6768 mL
20 mM0.1168 mL0.5838 mL1.1677 mL5.8384 mL
50 mM0.0467 mL0.2335 mL0.4671 mL2.3354 mL
100 mM0.0234 mL0.1168 mL0.2335 mL1.1677 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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