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Tat-βsyn-degron
🥰Excellent
Catalog No. TP3532Cas No. 2816095-52-8
Tat-βsyn-degron is an α-synuclein (α-synuclein) knockdown peptide that efficiently degrades the α-synuclein protein via the proteasome pathway. It effectively reduces α-synuclein protein levels in primary rat cortical neuron cultures. In Parkinson's mouse toxicity models, Tat-βsyn-degron alleviates neuronal damage and motor dysfunction induced by Parkinsonian toxins.
Tat-βsyn-degron
🥰Excellent
Catalog No. TP3532Cas No. 2816095-52-8
Tat-βsyn-degron is an α-synuclein (α-synuclein) knockdown peptide that efficiently degrades the α-synuclein protein via the proteasome pathway. It effectively reduces α-synuclein protein levels in primary rat cortical neuron cultures. In Parkinson's mouse toxicity models, Tat-βsyn-degron alleviates neuronal damage and motor dysfunction induced by Parkinsonian toxins.
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Bioactivity
Chemical Properties
| Description | Tat-βsyn-degron is an α-synuclein (α-synuclein) knockdown peptide that efficiently degrades the α-synuclein protein via the proteasome pathway. It effectively reduces α-synuclein protein levels in primary rat cortical neuron cultures. In Parkinson's mouse toxicity models, Tat-βsyn-degron alleviates neuronal damage and motor dysfunction induced by Parkinsonian toxins. |
| Molecular Weight | 3146.67 |
| Formula | C132H237N59O31 |
| Cas No. | 2816095-52-8 |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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