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(S)-Mandelic acid

Name: (S)-Mandelic acid
Brand: TargetMol
SKU: TYD-00568
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TYD-00568Cas No. 17199-29-0

(S)-Mandelic acid is the (S)-isomer of Mandelic Acid, exhibiting affinity activity (Ki=100 μM) for Aldo-keto reductase family 1 member B1.

(S)-Mandelic acid

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Purity: 98.83%

Catalog No. TYD-00568Cas No. 17199-29-0

(S)-Mandelic acid is the (S)-isomer of Mandelic Acid, exhibiting affinity activity (Ki=100 μM) for Aldo-keto reductase family 1 member B1.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
50 g	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:98.83%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	(S)-Mandelic acid is the (S)-isomer of Mandelic Acid, exhibiting affinity activity (Ki=100 μM) for Aldo-keto reductase family 1 member B1.
In vitro	(S)-Mandelic acid undergoes chiral inversion when incubated with intestinal bacteria of SD rats for 24 hours, converting to (R)-glycolic acid [1]. (S)-Mandelic acid undergoes chiral inversion when co-incubated with hepatocytes of SD rats for 2 hours, reverting to (R)-glycolic acid [1].
In vivo	After oral administration of a single dose of 100 mg/kg (S)-Mandelic acid to SD rats, the compound undergoes metabolic conversion in vivo to generate (R)-Glycolic acid [1].

Chemical Properties

Molecular Weight	152.15
Formula	C₈H₈O₃
Cas No.	17199-29-0
Smiles	O[C@H](C(O)=O)C1=CC=CC=C1
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 80.00 mg/mL (525.80 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.5725 mL	32.8623 mL	65.7246 mL	328.6231 mL
5 mM	1.3145 mL	6.5725 mL	13.1449 mL	65.7246 mL
10 mM	0.6572 mL	3.2862 mL	6.5725 mL	32.8623 mL
20 mM	0.3286 mL	1.6431 mL	3.2862 mL	16.4312 mL
50 mM	0.1314 mL	0.6572 mL	1.3145 mL	6.5725 mL
100 mM	0.0657 mL	0.3286 mL	0.6572 mL	3.2862 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc