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(Rac)-LM11A-31 dihydrochloride

Name: (Rac)-LM11A-31 dihydrochloride
Brand: TargetMol
SKU: T12669
Rating: 4.5 (1 reviews)

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Catalog No. T12669Cas No. 1214672-15-7

(Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride, a potent antagonist of proNGF (nerve growth factor).

(Rac)-LM11A-31 dihydrochloride

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Catalog No. T12669Cas No. 1214672-15-7

(Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride, a potent antagonist of proNGF (nerve growth factor).

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Product Introduction

Bioactivity

Description

(Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride, a potent antagonist of proNGF (nerve growth factor).

Chemical Properties

Molecular Weight	316.268
Formula	C₁₂H₂₇Cl₂N₃O₂
Cas No.	1214672-15-7
Smiles	Cl.Cl.CCC(C)C(N)C(=O)NCCN1CCOCC1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 200 mg/mL (632.38 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	3.1619 mL	15.8094 mL	31.6188 mL	158.0938 mL
5 mM	0.6324 mL	3.1619 mL	6.3238 mL	31.6188 mL
10 mM	0.3162 mL	1.5809 mL	3.1619 mL	15.8094 mL
20 mM	0.1581 mL	0.7905 mL	1.5809 mL	7.9047 mL
50 mM	0.0632 mL	0.3162 mL	0.6324 mL	3.1619 mL
100 mM	0.0316 mL	0.1581 mL	0.3162 mL	1.5809 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

LM11A-31 DihydrochlorideLM11A-31(Rac)-LM-11A-31 dihydrochloride(Rac)LM11A31 dihydrochloride(Rac) LM11A 31 dihydrochloride

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