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AC-099 hydrochloride

🥰Excellent
Catalog No. T83212Cas No. 849335-07-5

AC-099 hydrochloride is a selective full agonist of the neuropeptide FF2 receptor NPFF2R (EC50=1189 nM) and partial agonist function of the neuropeptide FF1 receptor NPFF1R (EC50=2370 nM) that reverses opioid-induced nociceptive sensitization, and may be used to study neurological....

AC-099 hydrochloride
Other Forms of AC-099 hydrochloride:
AC-099T83213849459-88-7
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AC-099 hydrochloride

🥰Excellent
Purity: 99.86%
Catalog No. T83212Cas No. 849335-07-5
AC-099 hydrochloride is a selective full agonist of the neuropeptide FF2 receptor NPFF2R (EC50=1189 nM) and partial agonist function of the neuropeptide FF1 receptor NPFF1R (EC50=2370 nM) that reverses opioid-induced nociceptive sensitization, and may be used to study neurological....
Pack SizePriceAvailabilityQuantity
5 mg$40In Stock
10 mg$64In Stock
25 mg$96In Stock
50 mg$129In Stock
100 mg$208In Stock
1 mL x 10 mM (in DMSO)$48In Stock
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Purity:99.86%
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Product Introduction

Bioactivity
Description
AC-099 hydrochloride is a selective full agonist of the neuropeptide FF2 receptor NPFF2R (EC50=1189 nM) and partial agonist function of the neuropeptide FF1 receptor NPFF1R (EC50=2370 nM) that reverses opioid-induced nociceptive sensitization, and may be used to study neurological....
In vivo
The NPFF2 agonist AC-099 (30 mg/kg; i.p.) exhibits activity in various pain models in vivo, whereas non-selective NPFF1 agonist administration increases sensitivity to both noxious and non-noxious stimuli[1].
Chemical Properties
Molecular Weight301.1
FormulaC9H9Cl2F3N4
Cas No.849335-07-5
SmilesCl.FC(F)(F)C1=CC(C=NNC(=N)N)=CC=C1Cl
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

NPFFR2NeuropeptideYReceptorNeuropeptide Y Receptor
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