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LGN-523
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Catalog No. T9901A-1295
Alias AML-01
LGN-523 (AML-01, IGN523) is a humanized monoclonal antibody targeting the human CD98 heavy chain (SLC3A2). Overexpressed in various tumors, particularly acute myeloid leukemia (AML), CD98 is involved in amino acid transport and integrin signaling. This antibody exerts anti-tumor activity by mediating potent ADCC, complement-dependent cytotoxicity (CDC), and inducing lysosomal membrane permeabilization.
LGN-523
LGN-523
Copy Product Info🥰Excellent
Catalog No. T9901A-1295Alias AML-01
LGN-523 (AML-01, IGN523) is a humanized monoclonal antibody targeting the human CD98 heavy chain (SLC3A2). Overexpressed in various tumors, particularly acute myeloid leukemia (AML), CD98 is involved in amino acid transport and integrin signaling. This antibody exerts anti-tumor activity by mediating potent ADCC, complement-dependent cytotoxicity (CDC), and inducing lysosomal membrane permeabilization.
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| Description | LGN-523 (AML-01, IGN523) is a humanized monoclonal antibody targeting the human CD98 heavy chain (SLC3A2). Overexpressed in various tumors, particularly acute myeloid leukemia (AML), CD98 is involved in amino acid transport and integrin signaling. This antibody exerts anti-tumor activity by mediating potent ADCC, complement-dependent cytotoxicity (CDC), and inducing lysosomal membrane permeabilization. |
| Synonyms | AML-01 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | CD98 |
| Isotype | IgG1 |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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