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Laurolitsine hydrochloride, an alkaloid extracted from Phoebe formosana, exhibits weak anti-inflammatory properties.
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| Description | Laurolitsine hydrochloride, an alkaloid extracted from Phoebe formosana, exhibits weak anti-inflammatory properties. |
| In vitro | Laurolitsine exhibits modest anti-inflammatory effects by inhibiting nitric oxide (NO) production in RAW 267.4 and BV-2 cells [1]. Concurrently, laurolitsine, along with boldine and litebamine at a concentration of 300 μM, significantly suppresses rabbit platelet aggregation triggered by arachidonic acid (100 μM) and collagen (10 μM/mL), while exhibiting a minor inhibition of aggregation induced by ADP (20 μM) [2]. |
| Synonyms | (+)-Norboldine hydrochloride |
| Formula | C18H20ClNO4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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