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PEG8000

Name: PEG8000
Brand: TargetMol
SKU: TCL-02181
Rating: 4.5 (1 reviews)

(Synonyms: Polyethylene glycol 8000, PEG 8000) Copy Product Info

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Synonyms: Polyethylene glycol 8000, PEG 8000

Catalog No. TCL-02181 Copy Product Info

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PEG8000 can be used for phage precipitation and plasmid DNA isolation, and it also effectively promotes DNA blunt-end ligation reactions.

PEG8000

Pack Size	Price	USA Stock	Global Stock	Quantity
10 mg	Inquiry	Inquiry	Inquiry
50 mg	Inquiry	Inquiry	Inquiry

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Appearance:Solid

Color:White

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Product Introduction

Bioactivity

Description	PEG8000 can be used for phage precipitation and plasmid DNA isolation, and it also effectively promotes DNA blunt-end ligation reactions.
In vitro	Methods: This review summarizes the FDA’s approved scope of application for PEG8000, its in vivo metabolic and excretion characteristics, and recent research progress regarding its immunogenicity. Results: PEG8000 has been approved by the FDA for use as a carrier or matrix in food, cosmetics, and various drug formulations, including injectable, topical, rectal, and intranasal dosage forms. PEG exhibits extremely low overall toxicity; molecules with a molecular weight <30 kDa are primarily excreted unchanged via the kidneys, while those >20 kDa are cleared via the fecal route. PEG itself is virtually non-immunogenic; it only induces the production of anti-PEG antibodies in rabbits when conjugated with highly immunogenic proteins [2].
Synonyms	Polyethylene glycol 8000, PEG 8000

Storage & Solubility Information

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	H2O: 80 mg/mL, Sonication is recommended. DMSO: 80 mg/mL, Sonication is recommended.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Related Tags: PEG8000 in vitro