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Flurocitabine HCl

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Catalog No. T27342LCas No. 40505-45-1
Alias Flurocitabine HCl(37717-21-8 Free base)

Flurocitabine HCl is a fluorinated anhydride analog of cytarabine, which is partially hydrolyzed in vivo to two active antitumor substances (arabinosyl-fluorouracil (ara-FC) and arabinosyl-fluorouracil (ara-FU)).Flurocitabine HCl has demonstrated antitumor activity in phase I studies in acute leukemia and solid tumors.

Flurocitabine HCl
Other Forms of Flurocitabine HCl:
FlurocitabineT2734237717-21-8
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Flurocitabine HCl

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Purity: 99.76%
Catalog No. T27342LAlias Flurocitabine HCl(37717-21-8 Free base)Cas No. 40505-45-1
Flurocitabine HCl is a fluorinated anhydride analog of cytarabine, which is partially hydrolyzed in vivo to two active antitumor substances (arabinosyl-fluorouracil (ara-FC) and arabinosyl-fluorouracil (ara-FU)).Flurocitabine HCl has demonstrated antitumor activity in phase I studies in acute leukemia and solid tumors.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$36In StockIn Stock
10 mg$52In StockIn Stock
25 mg$98In StockIn Stock
50 mg$132In StockIn Stock
100 mg$198In StockIn Stock
500 mg$470-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Purity:99.76%
ee:100%
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Product Introduction

Bioactivity
Description
Flurocitabine HCl is a fluorinated anhydride analog of cytarabine, which is partially hydrolyzed in vivo to two active antitumor substances (arabinosyl-fluorouracil (ara-FC) and arabinosyl-fluorouracil (ara-FU)).Flurocitabine HCl has demonstrated antitumor activity in phase I studies in acute leukemia and solid tumors.
SynonymsFlurocitabine HCl(37717-21-8 Free base)
Chemical Properties
Molecular Weight279.65
FormulaC9H11ClFN3O4
Cas No.40505-45-1
SmilesO[C@H]1[C@]2([C@](N3C(O2)=NC(=N)C(F)=C3)(O[C@@H]1CO)[H])[H].Cl
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 16.67 mg/mL (59.61 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.5759 mL17.8795 mL35.7590 mL178.7949 mL
5 mM0.7152 mL3.5759 mL7.1518 mL35.7590 mL
10 mM0.3576 mL1.7879 mL3.5759 mL17.8795 mL
20 mM0.1788 mL0.8940 mL1.7879 mL8.9397 mL
50 mM0.0715 mL0.3576 mL0.7152 mL3.5759 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

Flurocitabine HCl
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