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Urabrelimab (Synonyms: SRF-231, SRF231)
Catalog No. T76965 Copy Product Info
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Urabrelimab (SRF-231) is a humanized antibody targeting CD47, with antitumor activity. It blocks the CD47-SIRPα interaction and is used in studies of advanced malignant solid tumors.
Urabrelimab
Copy Product Info🥰Excellent
Catalog No. T76965
Synonyms SRF-231, SRF231
Urabrelimab (SRF-231) is a humanized antibody targeting CD47, with antitumor activity. It blocks the CD47-SIRPα interaction and is used in studies of advanced malignant solid tumors.
Urabrelimab
Cas No. 2249722-58-3
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $198 | In Stock | In Stock | |
| 5 mg | $579 | In Stock | In Stock | |
| 10 mg | $928 | - | In Stock | |
| 25 mg | $1,370 | - | In Stock | |
| 50 mg | $1,850 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:96% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Urabrelimab (SRF-231) is a humanized antibody targeting CD47, with antitumor activity. It blocks the CD47-SIRPα interaction and is used in studies of advanced malignant solid tumors. |
| In vitro | Urabrelimab specifically binds to human CD47 to induce phagocytosis in malignant B-cell lymphoma. Urabrelimab (10 μg/mL) induced tumor cell death in a CD32A-dependent manner. [1] |
| In vivo | Urabrelimab（100 μg, 3 times/week for 3 weeks) showed antitumor activity in a range of blood tumor xenotransplantation models. [1] |
| Synonyms | SRF-231, SRF231 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | CD47 |
| Molecular Weight | 145.44 kDa |
| Cas No. | 2249722-58-3 |
| Isotype | Human IgG4SP kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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