keep away from direct sunlight,store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
11-cis Retinal is a chromophore that binds to opsin in the mammalian visual system as an inverse agonist forming the inactive conformation of rhodopsin. When 11-cis retinal absorbs a photon of light, it isomerizes to form all-trans retinal beginning the phototransduction cycle, which is the basis for mammalian vision. A G121L mutation in opsin allows 11-cis retinal to bind as a partial agonist and activate rhodopsin in the absence of light. In a moth model of carotenoid deficiency-induced low visual sensitivity, 11-cis retinal application to compound eyes restored visual sensitivity almost completely.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 35 days | $ 6,720.00 |
Description | 11-cis Retinal is a chromophore that binds to opsin in the mammalian visual system as an inverse agonist forming the inactive conformation of rhodopsin. When 11-cis retinal absorbs a photon of light, it isomerizes to form all-trans retinal beginning the phototransduction cycle, which is the basis for mammalian vision. A G121L mutation in opsin allows 11-cis retinal to bind as a partial agonist and activate rhodopsin in the absence of light. In a moth model of carotenoid deficiency-induced low visual sensitivity, 11-cis retinal application to compound eyes restored visual sensitivity almost completely. |
Molecular Weight | 284.443 |
Formula | C20H28O |
CAS No. | 564-87-4 |
keep away from direct sunlight,store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Chloroform: Slightly Soluble
Methanol: Slightly Soluble
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11-cis Retinal 564-87-4 11cis Retinal 11 cis Retinal inhibitor inhibit