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(R)-3-Hydroxyisobutyric acid

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Catalog No. T19617Cas No. 1910-47-0
Alias (R)-2-Hydroxymethylpropanoic acid

(R)-3-Hydroxyisobutyric acid is a chiral organic compound and a metabolite derived from the amino acid L-valine and thymine catabolism. (R)-3-Hydroxyisobutyric acid is classified as a beta hydroxy acid and functions as a key intermediate in metabolic pathways involving L-valine and thymine. Elevated levels of (R)-3-Hydroxyisobutyric acid, also known as 3-HIBA, may serve as a diagnostic biomarker for severe inherited metabolic disorders, including 3-hydroxyisobutyric aciduria.

(R)-3-Hydroxyisobutyric acid
Other Forms of (R)-3-Hydroxyisobutyric acid:

(R)-3-Hydroxyisobutyric acid

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Purity: 97.149%
Catalog No. T19617Alias (R)-2-Hydroxymethylpropanoic acidCas No. 1910-47-0
(R)-3-Hydroxyisobutyric acid is a chiral organic compound and a metabolite derived from the amino acid L-valine and thymine catabolism. (R)-3-Hydroxyisobutyric acid is classified as a beta hydroxy acid and functions as a key intermediate in metabolic pathways involving L-valine and thymine. Elevated levels of (R)-3-Hydroxyisobutyric acid, also known as 3-HIBA, may serve as a diagnostic biomarker for severe inherited metabolic disorders, including 3-hydroxyisobutyric aciduria.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$30-In Stock
10 mg$38-In Stock
25 mg$59-In Stock
50 mg$85-In Stock
100 mg$123-In Stock
200 mg$183-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:97.149%
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Product Introduction

Bioactivity
Description
(R)-3-Hydroxyisobutyric acid is a chiral organic compound and a metabolite derived from the amino acid L-valine and thymine catabolism. (R)-3-Hydroxyisobutyric acid is classified as a beta hydroxy acid and functions as a key intermediate in metabolic pathways involving L-valine and thymine. Elevated levels of (R)-3-Hydroxyisobutyric acid, also known as 3-HIBA, may serve as a diagnostic biomarker for severe inherited metabolic disorders, including 3-hydroxyisobutyric aciduria.
Synonyms(R)-2-Hydroxymethylpropanoic acid
Chemical Properties
Molecular Weight104.1
FormulaC4H8O3
Cas No.1910-47-0
SmilesC[C@H](CO)C(O)=O
Relative Density.1.195g/cm3
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 100 mg/mL (960.61 mM), Sonication is recommended.
DMSO: 100 mg/mL (960.61 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM9.6061 mL48.0307 mL96.0615 mL480.3074 mL
5 mM1.9212 mL9.6061 mL19.2123 mL96.0615 mL
10 mM0.9606 mL4.8031 mL9.6061 mL48.0307 mL
20 mM0.4803 mL2.4015 mL4.8031 mL24.0154 mL
50 mM0.1921 mL0.9606 mL1.9212 mL9.6061 mL
100 mM0.0961 mL0.4803 mL0.9606 mL4.8031 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

Human Endogenous Metabolite3-Hydroxyisobutyric acid(R)3Hydroxyisobutyric acid(R) 3 Hydroxyisobutyric acid
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