Shopping Cart

Your shopping cart is currently empty

Fluanisone

Name: Fluanisone
Brand: TargetMol
SKU: T4275
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

🥰Excellent

Catalog No. T4275Cas No. 1480-19-9

Alias Sedalande, Haloanison

Fluanisone (Haloanison) is a butyrophenone derivative with sedative properties. It is a typical antipsychotic and is used in the treatment of schizophrenia.

Fluanisone

Copy Product Info

🥰Excellent

Purity: 99.94%

Catalog No. T4275Alias Sedalande, HaloanisonCas No. 1480-19-9

Fluanisone (Haloanison) is a butyrophenone derivative with sedative properties. It is a typical antipsychotic and is used in the treatment of schizophrenia.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$30	In Stock	In Stock
50 mg	$55	In Stock	In Stock
100 mg	$98	In Stock	In Stock
500 mg	$238	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$30	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.94%

Appearance:Solid

Color:White

Resource Download

COA LCMS HPLC HNMR

Product Introduction

Fluanisone AI Summary

Fluanisone demonstrates a wide range of bioactivities, including high affinity binding to multiple receptors and various pharmacological effects. It exhibits a high potency in displacing ligands from both the Dopamine receptor D2 (Ki = 2.9 nM) and the alpha-1 adrenergic receptor (Ki = 0.87 nM). It also shows moderate activity at the 5-hydroxytryptamine 2 receptor (Ki = 52.0 nM). The compound effectively suppresses conditioned avoidance behavior in rats and antagonizes apomorphine-induced climbing behavior in mice, with route-dependent efficacy (ED50 = 25.0 mg/kg orally and 0.4 mg/kg intraperitoneally). Additionally, it induces catalepsy in rats with an ED50 of 22.0 mg/kg intraperitoneally and modulates contractile activity and muscle tone in mice. Fluanisone also displays inhibitory activities against various enzymes and assays, including ALDH1A1, DNA Polymerase Beta, and 15-hLO-2, with varying potencies. Moreover, it possesses antiviral properties, inhibiting SARS-CoV-2 induced cytotoxicity in VERO-6 cells with an IC50 greater than 20,000 nM. The compound's pharmacokinetic properties are influenced by its logP (3.6) and logD7.4 (2.93) values, suggesting significant interactions with lipid environments..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Fluanisone (Haloanison) is a butyrophenone derivative with sedative properties. It is a typical antipsychotic and is used in the treatment of schizophrenia.
Synonyms	Sedalande, Haloanison

Chemical Properties

Molecular Weight	356.43
Formula	C₂₁H₂₅FN₂O₂
Cas No.	1480-19-9
Smiles	COC1=CC=CC=C1N1CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1
Relative Density.	1.146g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (140.28 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 2.5 mg/mL (7.01 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8056 mL	14.0280 mL	28.0560 mL	140.2800 mL
5 mM	0.5611 mL	2.8056 mL	5.6112 mL	28.0560 mL
10 mM	0.2806 mL	1.4028 mL	2.8056 mL	14.0280 mL
20 mM	0.1403 mL	0.7014 mL	1.4028 mL	7.0140 mL
50 mM	0.0561 mL	0.2806 mL	0.5611 mL	2.8056 mL
100 mM	0.0281 mL	0.1403 mL	0.2806 mL	1.4028 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc