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Levetimide

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Catalog No. T15741Cas No. 21888-99-3

Levetimide is a potent and stereoselective [3H](+)pentazocine binding inhibitor (Ki: 2.2 nM).

Levetimide

Levetimide

😃Good
Catalog No. T15741Cas No. 21888-99-3
Levetimide is a potent and stereoselective [3H](+)pentazocine binding inhibitor (Ki: 2.2 nM).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$9706-8 weeks6-8 weeks
50 mg$1,9806-8 weeks6-8 weeks
100 mg$2,5006-8 weeks6-8 weeks
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly
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Product Introduction

Bioactivity
Description
Levetimide is a potent and stereoselective [3H](+)pentazocine binding inhibitor (Ki: 2.2 nM).
In vitro
Although without stereoselectivity, Levetimide potently inhibits [3H]DTG binding (Ki: 103 nM) [1].
Chemical Properties
Molecular Weight362.46
FormulaC23H26N2O2
Cas No.21888-99-3
SmilesO=C1CC[C@](C2CCN(Cc3ccccc3)CC2)(C(=O)N1)c1ccccc1
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (275.89 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7589 mL13.7946 mL27.5893 mL137.9463 mL
5 mM0.5518 mL2.7589 mL5.5179 mL27.5893 mL
10 mM0.2759 mL1.3795 mL2.7589 mL13.7946 mL
20 mM0.1379 mL0.6897 mL1.3795 mL6.8973 mL
50 mM0.0552 mL0.2759 mL0.5518 mL2.7589 mL
100 mM0.0276 mL0.1379 mL0.2759 mL1.3795 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Levetimide
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