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Anthragallol
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Catalog No. T30086Cas No. 602-64-2
Alias Anthragallic acid, 1,2,3-Trihydroxyanthraquinone
Anthragallol (1,2,3-Trihydroxyanthraquinone) shows cytotoxicity by binding to DNA.Anthragallol can be used as an analytical reagent for the production of brown pickle colorants.
Anthragallol
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Purity: 99.73%
Catalog No. T30086Alias Anthragallic acid, 1,2,3-TrihydroxyanthraquinoneCas No. 602-64-2
Anthragallol (1,2,3-Trihydroxyanthraquinone) shows cytotoxicity by binding to DNA.Anthragallol can be used as an analytical reagent for the production of brown pickle colorants.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 2 mg | $33 | In Stock | In Stock | |
| 5 mg | $52 | In Stock | In Stock | |
| 10 mg | $77 | In Stock | In Stock | |
| 25 mg | $129 | In Stock | In Stock | |
| 50 mg | $193 | In Stock | In Stock | |
| 100 mg | $286 | In Stock | In Stock | |
| 500 mg | $693 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
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Purity:99.73%
Appearance:Solid
Color:Yellow
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Product Introduction
Anthragallol AI Summary
Anthragallol exhibits antifilarial activity, specifically targeting Brugia malayi (female) adult worms and Microfilaria. It shows significant potency in inducing mortality in these parasites at concentrations ranging from 3.125 ppm to 50 ppm, achieving 100% mortality of Brugia malayi female worms within 2.0 to 5.0 days at varying concentrations. Additionally, Anthragallol demonstrates bioactivity as an inhibitor of Bcl-2 and Mcl-1 with binding affinities of Ki = 583.0 nM and Ki = 270.0 nM, respectively, as per fluorescence polarization assay results after 30 minutes. However, different assay conditions report moderate binding affinities with Ki values of 1325.0 nM for Bcl-2 and 1211.0 nM for Mcl-1 using the displacement of FAM-Bid BH3 peptide in the fluorescence polarization assay after 10 minutes..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Anthragallol (1,2,3-Trihydroxyanthraquinone) shows cytotoxicity by binding to DNA.Anthragallol can be used as an analytical reagent for the production of brown pickle colorants. |
| Synonyms | Anthragallic acid, 1,2,3-Trihydroxyanthraquinone |
| Molecular Weight | 256.21 |
| Formula | C14H8O5 |
| Cas No. | 602-64-2 |
| Smiles | O=C1C=2C=CC=CC2C(=O)C3=C(O)C(O)=C(O)C=C13 |
| Relative Density. | 1.659g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 6.25 mg/mL (24.39 mM), Sonication is recommended.  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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