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Florfenicol

Name: Florfenicol
Brand: TargetMol
SKU: T0454
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0454Cas No. 76639-94-6

Alias Nuflor, Aquafen

Florfenicol (Aquafen) is a fluorinated synthetic analog of thiamphenicol. In the United States, florfenicol is currently used to treat bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) haemolytica, Pasteurella multocida, and Haemophilus somnus, to treat bovine interdigital phlegmon associated with Fusobacterium necrophorum and Bacteroides melaninogenicus.

Florfenicol

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Purity: 98.93%

Catalog No. T0454Alias Nuflor, AquafenCas No. 76639-94-6

Pack Size	Price	USA Warehouse	Global Warehouse
200 mg	$30	In Stock	In Stock
500 mg	$47	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:98.93%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Florfenicol (Aquafen) is a fluorinated synthetic analog of thiamphenicol. In the United States, florfenicol is currently used to treat bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) haemolytica, Pasteurella multocida, and Haemophilus somnus, to treat bovine interdigital phlegmon associated with Fusobacterium necrophorum and Bacteroides melaninogenicus.
In vitro	Florfenicol is found to stimulate algal growth at concentrations of 0.5, 1.0 and 2.0 mg/L, and significantly inhibit algal growth at >2.0 mg/L.
Synonyms	Nuflor, Aquafen

Chemical Properties

Molecular Weight	358.21
Formula	C₁₂H₁₄Cl₂FNO₄S
Cas No.	76639-94-6
Smiles	C(=O)(C(Cl)Cl)N[C@@H]([C@@H](c1ccc(cc1)S(=O)(=O)C)O)CF
Relative Density.	1.39g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 8 mg/mL (22.33 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 45 mg/mL (125.62 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7917 mL	13.9583 mL	27.9166 mL	139.5829 mL
5 mM	0.5583 mL	2.7917 mL	5.5833 mL	27.9166 mL
10 mM	0.2792 mL	1.3958 mL	2.7917 mL	13.9583 mL
20 mM	0.1396 mL	0.6979 mL	1.3958 mL	6.9791 mL

DMSO

	1mg	5mg	10mg	50mg
50 mM	0.0558 mL	0.2792 mL	0.5583 mL	2.7917 mL
100 mM	0.0279 mL	0.1396 mL	0.2792 mL	1.3958 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc