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Fmoc-Gln(Trt)-OH

🥰Excellent
Catalog No. TYD-00561Cas No. 132327-80-1

Fmoc-Gln(Trt)-OH is an N-Fmoc and O-Trityl protected derivative of glutamine utilized as a reagent in solid-phase peptide synthesis. Fmoc-Gln(Trt)-OH functions as a sulfonylation reagent in organic chemistry and as a biomaterial in biochemical research, providing a stable and reactive intermediate for constructing peptides and conjugates with high yield and purity.

Fmoc-Gln(Trt)-OH

Fmoc-Gln(Trt)-OH

🥰Excellent
Purity: 98.86%
Catalog No. TYD-00561Cas No. 132327-80-1
Fmoc-Gln(Trt)-OH is an N-Fmoc and O-Trityl protected derivative of glutamine utilized as a reagent in solid-phase peptide synthesis. Fmoc-Gln(Trt)-OH functions as a sulfonylation reagent in organic chemistry and as a biomaterial in biochemical research, providing a stable and reactive intermediate for constructing peptides and conjugates with high yield and purity.
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50 g$40-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.86%
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Product Introduction

Bioactivity
Description
Fmoc-Gln(Trt)-OH is an N-Fmoc and O-Trityl protected derivative of glutamine utilized as a reagent in solid-phase peptide synthesis. Fmoc-Gln(Trt)-OH functions as a sulfonylation reagent in organic chemistry and as a biomaterial in biochemical research, providing a stable and reactive intermediate for constructing peptides and conjugates with high yield and purity.
In vitro
During peptide chain synthesis, the use of Fmoc-protected glutamine derivative Fmoc-Gln(Trt)-OH can effectively suppress undesired side reactions of glutamine, thereby ensuring the accurate assembly of the peptide chain [2].
Chemical Properties
Molecular Weight610.7
FormulaC39H34N2O5
Cas No.132327-80-1
SmilesC(NC(CC[C@H](NC(OCC1C=2C(C=3C1=CC=CC3)=CC=CC2)=O)C(O)=O)=O)(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 80 mg/mL (131 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6375 mL8.1873 mL16.3747 mL81.8733 mL
5 mM0.3275 mL1.6375 mL3.2749 mL16.3747 mL
10 mM0.1637 mL0.8187 mL1.6375 mL8.1873 mL
20 mM0.0819 mL0.4094 mL0.8187 mL4.0937 mL
50 mM0.0327 mL0.1637 mL0.3275 mL1.6375 mL
100 mM0.0164 mL0.0819 mL0.1637 mL0.8187 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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