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Fmoc-Gln(Trt)-OH

Name: Fmoc-Gln(Trt)-OH
Brand: TargetMol
SKU: TYD-00561
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TYD-00561Cas No. 132327-80-1

Fmoc-Gln(Trt)-OH is an N-Fmoc and O-Trityl protected derivative of glutamine utilized as a reagent in solid-phase peptide synthesis. Fmoc-Gln(Trt)-OH functions as a sulfonylation reagent in organic chemistry and as a biomaterial in biochemical research, providing a stable and reactive intermediate for constructing peptides and conjugates with high yield and purity.

Fmoc-Gln(Trt)-OH

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Purity: 98.86%

Catalog No. TYD-00561Cas No. 132327-80-1

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
50 g	$40	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.86%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Fmoc-Gln(Trt)-OH is an N-Fmoc and O-Trityl protected derivative of glutamine utilized as a reagent in solid-phase peptide synthesis. Fmoc-Gln(Trt)-OH functions as a sulfonylation reagent in organic chemistry and as a biomaterial in biochemical research, providing a stable and reactive intermediate for constructing peptides and conjugates with high yield and purity.
In vitro	During peptide chain synthesis, the use of Fmoc-protected glutamine derivative Fmoc-Gln(Trt)-OH can effectively suppress undesired side reactions of glutamine, thereby ensuring the accurate assembly of the peptide chain [2].

Chemical Properties

Molecular Weight	610.7
Formula	C₃₉H₃₄N₂O₅
Cas No.	132327-80-1
Smiles	C(NC(CC[C@H](NC(OCC1C=2C(C=3C1=CC=CC3)=CC=CC2)=O)C(O)=O)=O)(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 80 mg/mL (131 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6375 mL	8.1873 mL	16.3747 mL	81.8733 mL
5 mM	0.3275 mL	1.6375 mL	3.2749 mL	16.3747 mL
10 mM	0.1637 mL	0.8187 mL	1.6375 mL	8.1873 mL
20 mM	0.0819 mL	0.4094 mL	0.8187 mL	4.0937 mL
50 mM	0.0327 mL	0.1637 mL	0.3275 mL	1.6375 mL
100 mM	0.0164 mL	0.0819 mL	0.1637 mL	0.8187 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc