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H-Leu-Leu-OMe . HBr

🥰Excellent
Catalog No. T36879L
Alias H-Leu-Leu-OMe . HBr (16689-14-8 Free base)

H-Leu-Leu-OMe . HBr is a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes. H-Leu-Leu-OMe . HBr induces endolysosomal pathway stress and selectively eliminates lymphocytes with cytotoxic potential.

H-Leu-Leu-OMe . HBr
Other Forms of H-Leu-Leu-OMe . HBr:
H-Leu-Leu-OMe HBrT3687916689-14-8
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H-Leu-Leu-OMe . HBr

🥰Excellent
Purity: 98.91%
Catalog No. T36879LAlias H-Leu-Leu-OMe . HBr (16689-14-8 Free base)
H-Leu-Leu-OMe . HBr is a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes. H-Leu-Leu-OMe . HBr induces endolysosomal pathway stress and selectively eliminates lymphocytes with cytotoxic potential.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$50-In Stock
10 mg$75-In Stock
25 mg$135-In Stock
50 mg$197-In Stock
100 mg$297-In Stock
200 mg$456-In Stock
1 mL x 10 mM (in DMSO)$74-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.91%
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COA MS HPLC

Product Introduction

Bioactivity
Description
H-Leu-Leu-OMe . HBr is a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes. H-Leu-Leu-OMe . HBr induces endolysosomal pathway stress and selectively eliminates lymphocytes with cytotoxic potential.
In vitro
H-Leu-Leu-OMe . HBr (10-250 μM; 15 min) is converted to a CCI3COOH-insoluble product by CD4- lymphocytes[1]. H-Leu-Leu-OMe . HBr (1 mM; 0.5-2 h) enhances LRRK2-mediated Rab10 and Rab12 phosphorylation in MEFs and A549 cells[2].
SynonymsH-Leu-Leu-OMe . HBr (16689-14-8 Free base)
Chemical Properties
Molecular Weight399.32
FormulaC15H31BrN2O5
SmilesCC(O)=O.O=C(OC)[C@@H](CC(C)C)NC([C@@H](N)CC(C)C)=O.Br
SequenceLeu-Leu
Sequence ShortLL
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (112.69 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5043 mL12.5213 mL25.0426 mL125.2129 mL
5 mM0.5009 mL2.5043 mL5.0085 mL25.0426 mL
10 mM0.2504 mL1.2521 mL2.5043 mL12.5213 mL
20 mM0.1252 mL0.6261 mL1.2521 mL6.2606 mL
50 mM0.0501 mL0.2504 mL0.5009 mL2.5043 mL
100 mM0.0250 mL0.1252 mL0.2504 mL1.2521 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

H-Leu-Leu-OMe . HBrHLeuLeuOMe . HBrH Leu Leu OMe . HBr16689-14-8 Free base16689-14-8
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