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5β-Cholanic acid

Name: 5β-Cholanic acid
Brand: TargetMol
SKU: T88859
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T88859Cas No. 546-18-9

Alias 5beta-Cholanic acid

5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.

5β-Cholanic acid

🥰Excellent

Purity: 99.89%

Catalog No. T88859Alias 5beta-Cholanic acidCas No. 546-18-9

5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.

Pack Size	Price	Availability
5 mg	$37	In Stock
10 mg	$58	In Stock
25 mg	$83	In Stock
1 mL x 10 mM (in DMSO)	$64	In Stock

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Batch Information

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Purity:99.89%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.
Synonyms	5beta-Cholanic acid

Chemical Properties

Molecular Weight	360.57
Formula	C₂₄H₄₀O₂
Cas No.	546-18-9
Smiles	C[C@@]12[C@]([C@]3([C@](CC1)([C@]4(C)[C@](CC3)(CCCC4)[H])[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]
Relative Density.	1.018 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL(221.87 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7734 mL	13.8669 mL	27.7339 mL	138.6693 mL
5 mM	0.5547 mL	2.7734 mL	5.5468 mL	27.7339 mL
10 mM	0.2773 mL	1.3867 mL	2.7734 mL	13.8669 mL
20 mM	0.1387 mL	0.6933 mL	1.3867 mL	6.9335 mL
50 mM	0.0555 mL	0.2773 mL	0.5547 mL	2.7734 mL
100 mM	0.0277 mL	0.1387 mL	0.2773 mL	1.3867 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc