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LH-RH, salmon acetate(86073-88-3 free base)

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Catalog No. TP1112L
Alias Luteinizing Hormone Releasing Hormone (LH-RH), salmon acetate

LH-RH, salmon acetate(86073-88-3 free base) (Luteinizing Hormone Releasing Hormone (LH-RH), salmon acetate) is a pituitary Hormone synthesized in the hypothalamus and plays a crucial role in the control of reproductive function.

LH-RH, salmon acetate(86073-88-3 free base)
Other Forms of LH-RH, salmon acetate(86073-88-3 free base):

LH-RH, salmon acetate(86073-88-3 free base)

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Purity: 99.83%
Catalog No. TP1112LAlias Luteinizing Hormone Releasing Hormone (LH-RH), salmon acetate
LH-RH, salmon acetate(86073-88-3 free base) (Luteinizing Hormone Releasing Hormone (LH-RH), salmon acetate) is a pituitary Hormone synthesized in the hypothalamus and plays a crucial role in the control of reproductive function.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$85In StockIn Stock
5 mg$183In StockIn Stock
10 mg$329In StockIn Stock
25 mg$592In StockIn Stock
50 mg$845In StockIn Stock
100 mg$1,170In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.83%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
LH-RH, salmon acetate(86073-88-3 free base) (Luteinizing Hormone Releasing Hormone (LH-RH), salmon acetate) is a pituitary Hormone synthesized in the hypothalamus and plays a crucial role in the control of reproductive function.
In vitro
Luteinizing hormone-releasing hormone (LHRH) is the key hormone in the control of reproductive functions.LHRH acts as an antimitogenic factor through the activation of the Gi-cAMP intracellular signaling pathway. LHRH might act as an inhibitory factor on both cell proliferation and metastatic behavior in melanoma cells[1]. The hypothalamic decapeptide luteinizing hormone-releasing hormone (LHRH) plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn promote gonadal functions and regulate sex steroid secretion. The effects of LHRH are mediated by high-affinity G protein-coupled LHRH-receptor (LHRH-R) on pituitary gonadotropes. The responses to LHRH vary under different conditions and critically depend on the regimens of administration and doses delivered to gonadotrope cells[2].
SynonymsLuteinizing Hormone Releasing Hormone (LH-RH), salmon acetate
Chemical Properties
Molecular Weight1272.35
FormulaC62H77N15O15
SmilesO=C([C@H]1NC(CC1)=O)N[C@@H](CC2=CN=CN2)C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC(C)C)C(N3[C@@H](CCC3)C(NCC(N)=O)=O)=O)=O)CC4=CNC5=CC=CC=C45)=O)=O)CC6=CC=C(C=C6)O)=O)=O)CC7=CNC8=CC=CC=C78)=O.CC(O)=O
Relative Density.no data available
Sequence{Glp}-His-Trp-Ser-Tyr-Gly-Trp-Leu-Pro-Gly-NH2
Sequence Short{Glp}-HWSYGWLPG
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10 mM, Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.7859 mL3.9297 mL7.8595 mL39.2974 mL
5 mM0.1572 mL0.7859 mL1.5719 mL7.8595 mL
10 mM0.0786 mL0.3930 mL0.7859 mL3.9297 mL

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TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

LH-RH, salmon acetate(86073-88-3 free base)LHRH, salmon acetate(86073883 free base)LH RH, salmon acetate(86073 88 3 free base)
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