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α-Guanidinoglutaric Acid

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Catalog No. T21526Cas No. 73477-53-9

α-Guanidinoglutaric Acid is found in cobalt-induced epileptogenic focus tissue in the cerebral cortex of cats. α-Guanidinoglutaric Acid-induced seizures are associated with abnormal serotonergic function and that they are initiated by a decrease in the 5-HT level.

α-Guanidinoglutaric Acid

α-Guanidinoglutaric Acid

😃Good
Purity: 99.73%
Catalog No. T21526Cas No. 73477-53-9
α-Guanidinoglutaric Acid is found in cobalt-induced epileptogenic focus tissue in the cerebral cortex of cats. α-Guanidinoglutaric Acid-induced seizures are associated with abnormal serotonergic function and that they are initiated by a decrease in the 5-HT level.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$50-In Stock
5 mg$59-In Stock
10 mg$84-In Stock
25 mg$148-In Stock
50 mg$215InquiryInquiry
100 mg$371InquiryInquiry
1 mL x 10 mM (in DMSO)$65-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.73%
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COA LCMS

Product Introduction

Bioactivity
Description
α-Guanidinoglutaric Acid is found in cobalt-induced epileptogenic focus tissue in the cerebral cortex of cats. α-Guanidinoglutaric Acid-induced seizures are associated with abnormal serotonergic function and that they are initiated by a decrease in the 5-HT level.
In vivo
α-Guanidinoglutaric Acid induced epileptic seizures in rats after intraventricular administration. Sporadic low-voltage spikes appeared 4 min after the administration of α-Guanidinoglutaric Acid. Spikes increased in voltage 6 min after the administration.
Chemical Properties
Molecular Weight189.17
FormulaC6H11N3O4
Cas No.73477-53-9
SmilesNC(=N)N[C@@H](CCC(O)=O)C(O)=O
Relative Density.1.62 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (290.74 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.2863 mL26.4313 mL52.8625 mL264.3125 mL
5 mM1.0573 mL5.2863 mL10.5725 mL52.8625 mL
10 mM0.5286 mL2.6431 mL5.2863 mL26.4313 mL
20 mM0.2643 mL1.3216 mL2.6431 mL13.2156 mL
50 mM0.1057 mL0.5286 mL1.0573 mL5.2863 mL
100 mM0.0529 mL0.2643 mL0.5286 mL2.6431 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

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