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α-Guanidinoglutaric Acid

Name: α-Guanidinoglutaric Acid
Brand: TargetMol
SKU: T21526
Price: 50 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T21526Cas No. 73477-53-9

α-Guanidinoglutaric Acid is found in cobalt-induced epileptogenic focus tissue in the cerebral cortex of cats. α-Guanidinoglutaric Acid-induced seizures are associated with abnormal serotonergic function and that they are initiated by a decrease in the 5-HT level.

α-Guanidinoglutaric Acid

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Purity: 99.73%

Catalog No. T21526Cas No. 73477-53-9

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$50	-	In Stock
5 mg	$59	-	In Stock
10 mg	$84	-	In Stock
25 mg	$148	-	In Stock
50 mg	$215	Inquiry	Inquiry
100 mg	$371	Inquiry	Inquiry
1 mL x 10 mM (in DMSO)	$65	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.73%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	α-Guanidinoglutaric Acid is found in cobalt-induced epileptogenic focus tissue in the cerebral cortex of cats. α-Guanidinoglutaric Acid-induced seizures are associated with abnormal serotonergic function and that they are initiated by a decrease in the 5-HT level.
In vivo	α-Guanidinoglutaric Acid induced epileptic seizures in rats after intraventricular administration. Sporadic low-voltage spikes appeared 4 min after the administration of α-Guanidinoglutaric Acid. Spikes increased in voltage 6 min after the administration.

Chemical Properties

Molecular Weight	189.17
Formula	C₆H₁₁N₃O₄
Cas No.	73477-53-9
Smiles	NC(=N)N[C@@H](CCC(O)=O)C(O)=O
Relative Density.	1.62 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (290.74 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.2863 mL	26.4313 mL	52.8625 mL	264.3125 mL
5 mM	1.0573 mL	5.2863 mL	10.5725 mL	52.8625 mL
10 mM	0.5286 mL	2.6431 mL	5.2863 mL	26.4313 mL
20 mM	0.2643 mL	1.3216 mL	2.6431 mL	13.2156 mL
50 mM	0.1057 mL	0.5286 mL	1.0573 mL	5.2863 mL
100 mM	0.0529 mL	0.2643 mL	0.5286 mL	2.6431 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc