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Cliramitug

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Catalog No. T9901A-905Cas No. 2965214-50-8
Alias NI006

Cliramitug is a monoclonal antibody that targets human transthyretin protein (TTR). By binding to TTR, Cliramitug inhibits its amyloid formation process and exhibits activity that prevents amyloid deposition. Cliramitug holds potential for research in transthyretin amyloidosis-related diseases, including certain neurological and cardiovascular conditions.

Cliramitug

Cliramitug

😃Good
Catalog No. T9901A-905Alias NI006Cas No. 2965214-50-8
Cliramitug is a monoclonal antibody that targets human transthyretin protein (TTR). By binding to TTR, Cliramitug inhibits its amyloid formation process and exhibits activity that prevents amyloid deposition. Cliramitug holds potential for research in transthyretin amyloidosis-related diseases, including certain neurological and cardiovascular conditions.
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Instruction Manual of Inhibitory Antibody

Product Introduction

Bioactivity
Description
Cliramitug is a monoclonal antibody that targets human transthyretin protein (TTR). By binding to TTR, Cliramitug inhibits its amyloid formation process and exhibits activity that prevents amyloid deposition. Cliramitug holds potential for research in transthyretin amyloidosis-related diseases, including certain neurological and cardiovascular conditions.
SynonymsNI006
Reactivity
Human
Application
ELISA
FACS
Functional assay
Antibody Type
Monoclonal
Endotoxin＜ 1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
P02766
TargetTTR
Chemical Properties
Cas No.2965214-50-8
Antibody Information
IsotypeIgG2SA
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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