Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50 = 15 nM) on neurons at the neuromuscular junction, causing the channel to open irreversibly at potentials more negative than normal, discharging action potentials repetitively. Brevetoxin B is ichthyotoxic at nanomolar concentrations and is responsible for an illness described as neurotoxic shellfish poisoning.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 35 days | $ 688.00 |
Description | Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50 = 15 nM) on neurons at the neuromuscular junction, causing the channel to open irreversibly at potentials more negative than normal, discharging action potentials repetitively. Brevetoxin B is ichthyotoxic at nanomolar concentrations and is responsible for an illness described as neurotoxic shellfish poisoning. |
Molecular Weight | 895.096 |
Formula | C50H70O14 |
CAS No. | 79580-28-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethyl Acetate: Soluble
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Brevetoxin B 79580-28-2 inhibitor inhibit