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RC-3095 acetate
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Catalog No. TP2153Cas No. 162666-31-1
RC-3095 acetate is an antagonist of bombesin/gastrin-releasing peptide receptor (GRPR). It exerts protective effects by reducing gastric oxidative injury in the arthritic mice.
RC-3095 acetate
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Catalog No. TP2153Cas No. 162666-31-1
RC-3095 acetate is an antagonist of bombesin/gastrin-releasing peptide receptor (GRPR). It exerts protective effects by reducing gastric oxidative injury in the arthritic mice.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 mg | Inquiry | Backorder | |
| 500 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | RC-3095 acetate is an antagonist of bombesin/gastrin-releasing peptide receptor (GRPR). It exerts protective effects by reducing gastric oxidative injury in the arthritic mice. |
| In vivo | RC-3095 impairs aversive but not recognition memory in Wistar male rats [1]. RC-3095 (0.3 mg/kg or 1 mg/kg; S.C.) shows anti-inflammatory effects in 2 experimental models of arthritis, collagen-induced arthritis, and antigen-induced arthritis. Arthritic mice treated with RC-3095 show a significant reduction in the concentrations of IL-1, IL-17, and TNF, and showed a diminished expression of GRPR [2]. |
| Molecular Weight | 1166.396 |
| Formula | C58H83N15O11 |
| Cas No. | 162666-31-1 |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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