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2,3-Benzofluorene
🥰Excellent
Catalog No. TN9183Cas No. 243-17-4
Alias Benzo[b]fluorene, 11H-Benzo[b]fluorene
2,3-Benzofluorene (Benzo[b]fluorene) is a useful life science reagent for biochemical experiments and organic synthesis.
2,3-Benzofluorene
🥰Excellent
Catalog No. TN9183Alias Benzo[b]fluorene, 11H-Benzo[b]fluoreneCas No. 243-17-4
2,3-Benzofluorene (Benzo[b]fluorene) is a useful life science reagent for biochemical experiments and organic synthesis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $195 | In Stock | |
| 5 mg | $483 | In Stock | |
| 10 mg | $692 | In Stock | |
| 25 mg | $1,080 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | 2,3-Benzofluorene (Benzo[b]fluorene) is a useful life science reagent for biochemical experiments and organic synthesis. |
| In vivo | In Sprague Dawley rats, oral administration of 2,3-Benzofluorene for 5 consecutive days (0-1000 mg/kg) caused dose-dependent effects. In males, increased TSH and decreased thyroxine were observed (lowest BMD: 11.8 mg/kg), while in females, increased liver weight and cholesterol were noted (lowest BMD: 1.08 mg/kg). Transcriptomic analysis revealed significant changes in liver and kidney gene expression, with the most sensitive gene showing a BMD as low as 0.96 mg/kg, indicating strong in vivo activity with higher sensitivity in female rats[1]. |
| Alias | Benzo[b]fluorene, 11H-Benzo[b]fluorene |
| Molecular Weight | 216.28 |
| Formula | C17H12 |
| Cas No. | 243-17-4 |
| Smiles | C=1C=CC=2C=C3C(=CC2C1)C=4C=CC=CC4C3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Sci Citations
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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