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7-Cyano-7-deazaguanine

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Catalog No. TN7185Cas No. 69205-79-4

Alias 7-CN-7-deazaG

7-Cyano-7-deazaguanine (7-CN-7-deazaG) is a marine derived natural products found in Streptomyces qinglanensis.

7-Cyano-7-deazaguanine

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Purity: 99.92%

Catalog No. TN7185Alias 7-CN-7-deazaGCas No. 69205-79-4

7-Cyano-7-deazaguanine (7-CN-7-deazaG) is a marine derived natural products found in Streptomyces qinglanensis.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$50	In Stock	In Stock
10 mg	$75	In Stock	In Stock
25 mg	$128	In Stock	-
50 mg	$192	In Stock	-
100 mg	$287	Inquiry	Inquiry
200 mg	$431	Inquiry	Inquiry
1 mL x 10 mM (in DMSO)	$55	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.92%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

7-Cyano-7-deazaguanine AI Summary

7-Cyano-7-deazaguanine shows moderate bioactivity as an inhibitor of Trypanosoma brucei recombinant PTR1, with a Ki value of 5800.0 nM, indicating its potential effectiveness in inhibiting this enzyme. However, it exhibits relatively low bioactivity against Leishmania major recombinant PTR1, with a Ki value greater than 27000.0 nM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	7-Cyano-7-deazaguanine (7-CN-7-deazaG) is a marine derived natural products found in Streptomyces qinglanensis.
Synonyms	7-CN-7-deazaG

Chemical Properties

Molecular Weight	175.15
Formula	C₇H₅N₅O
Cas No.	69205-79-4
Smiles	Nc1nc2[nH]cc(C#N)c2c(=O)[nH]1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 9 mg/mL (51.38 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.7094 mL	28.5470 mL	57.0939 mL	285.4696 mL
5 mM	1.1419 mL	5.7094 mL	11.4188 mL	57.0939 mL
10 mM	0.5709 mL	2.8547 mL	5.7094 mL	28.5470 mL
20 mM	0.2855 mL	1.4273 mL	2.8547 mL	14.2735 mL
50 mM	0.1142 mL	0.5709 mL	1.1419 mL	5.7094 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc