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Methyl 3,5-dihydroxybenzoate

Name: Methyl 3,5-dihydroxybenzoate
Brand: TargetMol
SKU: T1355
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1355Cas No. 2150-44-9

Methyl 3, 5-dihydroxybenzoate was used in the synthesis of cored dendrimers.

Methyl 3,5-dihydroxybenzoate

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Purity: 99.68%

Catalog No. T1355Cas No. 2150-44-9

Methyl 3, 5-dihydroxybenzoate was used in the synthesis of cored dendrimers.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.68%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Methyl 3,5-dihydroxybenzoate AI Summary

Methyl 3,5-dihydroxybenzoate exhibits a diverse range of biological activities. It demonstrates antifeedant activity against the pine weevil (Hylobius abietis) in pre-treated Scots pine twigs at a concentration of 50 mM, achieving a 23.0% Antifeedant Index (AFI) after 24 hours in a two-choice laboratory bioassay. The compound also shows significant antibacterial activity against Ralstonia solanacearum, producing an inhibition zone of 18.0 mm when tested at a concentration of 5 µmol/disk using the paper disk method on potato semi-synthetic agar medium. Additionally, Methyl 3,5-dihydroxybenzoate acts as an inhibitor of various human carbonic anhydrase isoforms, with Ki values ranging from 690.0 nM to 840.0 nM, indicating potential utility in targeting different physiological functions mediated by these enzymes. Moreover, it displays trypanosomicidal activity against the epimastigote stage of Trypanosoma cruzi CL-B5, with an IC50 greater than 256,000.0 nM, and exhibits cytotoxicity against mouse J774 cells with an IC50 also greater than 256,000.0 nM as measured by the resazurin assay after 48 hours..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

Methyl 3, 5-dihydroxybenzoate was used in the synthesis of cored dendrimers.

Chemical Properties

Molecular Weight	168.15
Formula	C₈H₈O₄
Cas No.	2150-44-9
Smiles	COC(=O)C1=CC(O)=CC(O)=C1
Relative Density.	1.354 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 45 mg/mL (267.62 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.9471 mL	29.7354 mL	59.4707 mL	297.3536 mL
5 mM	1.1894 mL	5.9471 mL	11.8941 mL	59.4707 mL
10 mM	0.5947 mL	2.9735 mL	5.9471 mL	29.7354 mL
20 mM	0.2974 mL	1.4868 mL	2.9735 mL	14.8677 mL
50 mM	0.1189 mL	0.5947 mL	1.1894 mL	5.9471 mL
100 mM	0.0595 mL	0.2974 mL	0.5947 mL	2.9735 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc